Journal
ORGANIC LETTERS
Volume 20, Issue 1, Pages 64-67Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b03358
Keywords
-
Categories
Funding
- NSFC [21502192, 21402199]
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDB20000000]
- Chinese Recruitment Program of Global Experts
Ask authors/readers for more resources
The umpolung of beta,gamma-unsaturated diketones through N-heterocyclic carbene catalysis is described, which allows access to a variety of highly functionalized bicyclic cydohexene-beta-lactones and 1,3,4-triaryl benzenes. An unprecedented reaction pattern involving the catalytic formation of nucleophilic O-acylated homoenolate intermediate is proposed. A diverse set of transformations on the product further showed the synthetic potential of this protocol.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
