Journal
ORGANIC LETTERS
Volume 19, Issue 13, Pages 3486-3489Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b01468
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Funding
- Ministry of Science and Technology (MOST), Taiwan [MOST 105-2628-B-197-001-MY3]
- Taiwan International Graduate Program (TIGP), Academia Sinica
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Galactomannan with an octasaccharide-repeating unit (ACP) was isolated from Taiwan medicinal mushroom Antrodia cinnamomea, and its chemical structure was determined herein. ACP significantly enhanced the phagocytosis and bactericidal activity of J774A.1 murine macrophages against Escherichia coli, with prospects for developing a new immunomodulatory compound or adjuvant in immunotherapy and vaccination.
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