Journal
ORGANIC LETTERS
Volume 19, Issue 12, Pages 3271-3274Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b01411
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Funding
- National Natural Science Foundation [21372106]
- Program 111
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The N-heterocyclic carbene-catalyzed asymmetric Michael/aldol/lactamization cascade reaction of enals and indole-derived enones for the synthesis of functionalized cyclopenta[3,4]pyrroloindolones with four consecutive stereogenic centers has been achieved. The products were obtained in good yield with high diastereoselectivity and excellent enantioselectivity.
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