Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 15, Issue 26, Pages 5457-5461Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob01277b
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- UGC, New Delhi
- CSIR-New Delhi [BSC0108]
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An efficient Ru(II)-catalyzed site-selective C-H arylation of 2-pyridones and 1-isoquinolinones was achieved with boronic acids by using pyridine as a directing group. The developed protocol is general and provides rapid access to an array of C6-arylated 2-pyridones and C3-arylated 1-isoquinolinones in excellent yields. These designed arylated 2-pyridones and 1-isoquinolinones can serve as key structural motifs for accessing functionalized pyridines and isoquinolines.
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