4.6 Review

Recent progress in transition-metal-catalyzed enantioselective indole functionalizations

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 15, Issue 17, Pages 3550-3567

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob00413c

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Funding

  1. National Natural Science Foundation of China [21372202, 21522207]
  2. Natural Science Foundation of Zhejiang Province [LR14B020001]

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Numerous efficient synthetic methods for enantioselective indole functionalizations have emerged in recent years. This review summarizes the major achievements in the transition-metal-catalyzed enantioselective indole functionalization reactions since 2010 and focuses on C-C bond formation processes, including alkylations, arylations, cycloaddition reactions, and other reactions. It intends to give a compendious overview of the significant progress achieved in this area.

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