Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 15, Issue 15, Pages 3130-3151Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob00405b
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- Council of Scientific and Industrial Research (CSIR), New Delhi
- CSIR, New Delhi [CSC-0108]
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ipso-Annulation represents an attractive approach to synthesize a variety of spirocyclic compounds having a quaternary carbon center. Furthermore, these compounds also serve as a handy synthon for the construction of various complex molecules. This review presents various useful approaches for the intramolecular ipso-cyclization to afford a wide range of spirocyclohexadienones. In addition, the utility of spirocyclic compounds towards the synthesis of complex molecules is also included.
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