4.6 Article

Heptafluoroisopropyl diazomethane (i-C3F7CHN2): in situ generation and synthesis of pyrazoles

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 15, Issue 35, Pages 7296-7301

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob01579h

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A novel chemical reagent - heptafluoroisopropyl diazomethane (i-C3F7CHN2) - has been generated in situ in aqueous media. It readily reacts with electron-deficient alkynes towards polyfluorinated pyrazoles that are important in agrochemistry.

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