Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 15, Issue 10, Pages -Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ob02352e
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Funding
- Natural Science Foundation of Zhejiang Province [LY14B020009]
- National Natural Science Foundation of China [21572162, 21472140, 21272176]
- Science and Technology Project of Zhejiang Province [2016C31022]
- Xinmiao Talent Planning Foundation of Zhejiang Province [2015R426061, 2016R426058, 2016R426059]
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The first example of a copper-catalyzed halogen-free protocol to construct indazolo[3,2-b]quinazolinones was developed through sequential inert C-O bond cleavage followed by intramolecular C-N bond formation. This protocol represents an efficient synthetic tool for accessing a more diverse range of functionalized indazolo[3,2-b]quinazolinones. The structure of the newly synthesized indazolo[3,2-b] quinazolinones was unambiguously confirmed by X-ray crystal diffraction analysis.
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