Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 15, Issue 26, Pages 5549-5555Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob01160a
Keywords
-
Categories
Funding
- Okayama Foundation for Science and Technology
- Yakumo Foundation for Environmental Science
- Grants-in-Aid for Scientific Research [17K05862, 17K05863] Funding Source: KAKEN
Ask authors/readers for more resources
Hybrid molecules consisting of geraniol and butenolide were designed and synthesized by the late-stage divergent strategy. In the synthetic route, ring-closing metathesis was utilized for the construction of a butenolide moiety. A biological evaluation of the eight synthetic hybrid compounds revealed that these molecules exhibit antifouling activity against the cypris larvae of the barnacle Balanus (Amphibalanus) amphitrite with EC50 values of 0.30-1.31 mu g mL(-1). These results show that hybridization of the geraniol and butenolide structural motifs resulted in the enhancement of the antifouling activity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available