Journal
OPTICS LETTERS
Volume 42, Issue 7, Pages 1233-1236Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.42.001233
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Funding
- Australian Research Council (ARC)
- National Health and Medical Research Council (NHMRC)
- National Breast Cancer Foundation (NBCF)
- Department of Health, Government of Western Australia
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Depth-encoded optical coherence elastography (OCE) enables simultaneous acquisition of two three-dimensional (3D) elastograms from opposite sides of a sample. By the choice of suitable path-length differences in each of two interferometers, the detected carrier frequencies are separated, allowing depth-ranging from each interferometer to be performed simultaneously using a single spectrometer. We demonstrate depth-encoded OCE on a silicone phantom and a freshly excised sample of mouse liver. This technique minimizes the required spectral detection hardware and halves the total scan time. Depth-encoded OCE may expedite clinical translation in time-sensitive applications requiring rapid 3D imaging of multiple tissue surfaces, such as tumor margin assessment in breast-conserving surgery. (C) 2017 Optical Society of America
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