Journal
OPTICS LETTERS
Volume 42, Issue 15, Pages 2938-2940Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.42.002938
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Funding
- National Natural Science Foundation of China (NSFC) [81370505, 81571744, 81370591]
- Ministry of Health Foundation for State Key Clinical Department
- 863 program in China [2012AA02A201, 2015AA020502, 2015CB553800]
- 973 program in China [2012AA02A201, 2015AA020502, 2015CB553800]
- Fundamental Research Funds for the Central Universities [20720170065, 20720170036]
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Homeostasis of the gut microbiota is indispensable for various physiological functions. Its composition and activity co-develop with the host, and especially associate with human colorectal cancer. However, current composition identification methods are complicated and not timely without spatial distribution information. In this Letter, we explored the photoacoustic imaging (PAI) technique to characterize the composition and quantify the proportions of the gut microbes after optical probe labeling. Our experimental results demonstrated that PAI has the potential to identify different gut bacterial species on the spot. (C) 2017 Optical Society of America
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