Journal
OPTICS LETTERS
Volume 42, Issue 16, Pages 3193-3196Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.42.003193
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Funding
- National Institutes of Health (NIH) [F32-CA183400, R01-CA075289, R01-CA178636, R01-EY011289, R44-CA101067]
- Air Force Office of Scientific Research (AFOSR) [FA9550-12-1-0499, FA9550-15-1-0473]
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Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 mu m field of view and 5 mu m transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe is 3.3 mm diameter and 20 mm rigid length, thus enabling passage through the endoscopic channel. The scanner has 1.8 kHz resonant frequency, and each volumetric acquisition takes 0.17 s with 2 volumes/s display. 3D-OCT and angiography imaging of the colon was performed during surveillance colonoscopy. (C) 2017 Optical Society of America
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