Prevalence of and factors related to anxiety and depression symptoms among married patients with gynecological malignancies in China

Objective: This study aims to investigate the prevalence of anxiety and depression among married patients with gynecological malignancies in China and then explores factors related to anxiety and depression. Methods: A cross-sectional study was conducted from July 2016 to July 2017 in Jilin Province. A total of 394 married patients with gynecological malignancies completed the Hospital Anxiety and Depression Scale (HADS). Univariate analysis and multivariate logistic regression analysis were used to evaluate the association between influencing factors of anxiety and depression. Back propagation neural networks (BP neural networks) were used to examine the ranking of these influencing factors. Results: The prevalence of anxiety and depression was 79.95% and 94.16% in married patients with gynecological malignancies. Multivariate logistic analysis revealed that patients' anxiety showed significant relationships with low income, frequency of chemotherapy, diagnostic results and low sleep quality(P < 0.05), and patients' depression showed significant relationships with low quality sleep and frequency of chemotherapy (P < 0.05). Using BP neural networks, the order of importance of these factors in influencing anxiety, from high to low, was determined to be sleep quality, frequency of chemotherapy, monthly income, diagnostic results, age and fertility demand. Conclusions: It is important to reduce anxiety and depression in these patients by improving sleep quality and clinical treatment.