4.5 Review

Cancer drug delivery in the nano era: An overview and perspectives (Review)

Journal

ONCOLOGY REPORTS
Volume 38, Issue 2, Pages 611-624

Publisher

SPANDIDOS PUBL LTD
DOI: 10.3892/or.2017.5718

Keywords

nanoparticles; drug carriers; cancer treatment; delivery system; clinical trials

Categories

Funding

  1. Scholarship Award for Excellent Doctoral Student Granted of Yunnan Province [6011418150]
  2. Foundation of Leading Talent Program of Health and Family Planning Commission of Yunnan Province [L-201205]
  3. Foundation of Institute of Gastroenterology, Research institutions attached to Health and Family Planning Commission of Yunnan Province [2014NS122]

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Nanomaterials are increasingly used as drug carriers for cancer therapy. Nanomaterials also appeal to researchers in the areas of cancer diagnosis and biomarker discovery. Several antitumor nanodrugs are currently being tested in preclinical and clinical trials and show promise in therapeutic and other settings. We review the development of nanomaterial drug carriers, including liposomes, polymer nanoparticles, dendritic polymers, and nanomicelles, for the diagnosis and treatment of various cancers. The prospects of nanomaterials as drug carriers for future clinical applications are also discussed.

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