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Expression of γ-H2AX in melanocytic lesions
Matthew J. Wasco et al.
HUMAN PATHOLOGY (2008)
MTOR is activated in the majority of malignant melanomas
Magdalena Karbowniczek et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. Christofk et al.
NATURE (2008)
C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells
D. Zhuang et al.
ONCOGENE (2008)
BRAFE600 in benign and malignant human tumours
C. Michaloglou et al.
ONCOGENE (2008)
Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi
Debdutta Bandyopadhyay et al.
AGING CELL (2007)
Expression of activated Akt in benign nevi, Spitz nevi and melanomas
Sara M. Kantrow et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2007)
Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft
Silvina Gazzaniga et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)
Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo
Veronique Bataille et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2007)
Melanocytic skin lesions and pregnancy: digital dermoscopy analysis
Pietro Rubegni et al.
SKIN RESEARCH AND TECHNOLOGY (2007)
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue et al.
NATURE (2007)
Epigenetic silencing of novel tumor suppressors in malignant melanoma
Viswanathan Muthusamy et al.
CANCER RESEARCH (2006)
A negative feedback signaling network underlies oncogene-induced senescence
Stephanie Courtois-Cox et al.
CANCER CELL (2006)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
Raffaella Di Micco et al.
NATURE (2006)
Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway
Christophe Denoyelle et al.
NATURE CELL BIOLOGY (2006)
Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
V. C. Gray-Schopfer et al.
BRITISH JOURNAL OF CANCER (2006)
BRAF and NRAS mutations in melanoma and melanocytic nevi
Jenny N. Poynter et al.
MELANOMA RESEARCH (2006)
Mechanisms of disease - Melanoma
Arlo J. Miller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Senescence-associated β-galactosidase is lysosomal β-galactosidase
BY Lee et al.
AGING CELL (2006)
Immunohistological characterisation of tumour infiltrating lymphocytes in melanocytic skin lesions
MR Hussein et al.
JOURNAL OF CLINICAL PATHOLOGY (2006)
Implication of MT1-MMP in the maturation steps of benign melanocytic nevi
LJ Pérez et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2006)
Ultraviolet radiation at places of residence and the development of melanocytic nevi in children (Australia)
DR English et al.
CANCER CAUSES & CONTROL (2006)
Lack of association between BRAF mutation and MAPK ERK activation in melanocytic nevi
Pablo Uribe et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)
Cutaneous melanoma susceptibility and progression genes
FA de Snoo et al.
CANCER LETTERS (2005)
Distinct sets of genetic alterations in melanoma
JA Curtin et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Activation of the extracellular signal regulated kinase (ERK) pathway in human melanoma
L Zhuang et al.
JOURNAL OF CLINICAL PATHOLOGY (2005)
Mutational analysis of the BRAF gene in human congenital and dysplastic melanocytic naevi
T Papp et al.
MELANOMA RESEARCH (2005)
BRAFE600-associated senescence-like cell cycle arrest of human naevi
C Michaloglou et al.
NATURE (2005)
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
VG Gorgoulis et al.
NATURE (2005)
Prognostic significance of activated Akt expression in melanoma: A clinicopathologic study of 292 cases
DL Dai et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma
EE Patton et al.
CURRENT BIOLOGY (2005)
Proliferation, apoptosis, and survivin expression in a spectrum of melanocytic nevi
SR Florell et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2005)
Meta-analysis of risk factors for cutaneous melanoma: I. Common and atypical naevi
S Gandini et al.
EUROPEAN JOURNAL OF CANCER (2005)
Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma
H Tsao et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)
Longitudinal assessment of the nevus phenotype in a melanoma kindred
SR Florell et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)
Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT
AM Mirza et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Deregulated Akt3 activity promotes development of malignant melanoma
JM Stahl et al.
CANCER RESEARCH (2004)
Cutaneous melanomas associated with nevi
C Bevona et al.
ARCHIVES OF DERMATOLOGY (2003)
Eruptive melanocytic nevi in patients with renal allografts: Report of 10 cases with dermoscopic findings
M Alaibac et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2003)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
Grading of atypia in nevi: Correlation with melanoma risk
M Arumi-Uria et al.
MODERN PATHOLOGY (2003)
Association of increased autophagic inclusions labeled for β-galactosidase with fibroblastic aging
LM Gerland et al.
EXPERIMENTAL GERONTOLOGY (2003)
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
M Narita et al.
CELL (2003)
Acquired melanocytic nevi as risk factor for melanoma development. A comprehensive review of epidemiological data
J Bauer et al.
PIGMENT CELL RESEARCH (2003)
Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer
BC Bastian
ONCOGENE (2003)
Hypothesis: A role for telomere crisis in spontaneous regression of melanoma
BC Bastian
ARCHIVES OF DERMATOLOGY (2003)
Early melanoma detection: Nonuniform dermoscopic features and growth
CR Lucas et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2003)
Melanoma ex naevo:: a study of the associated naevus
I Bogdan et al.
MELANOMA RESEARCH (2003)
The transformation rate of moles (melanocytic nevi) into cutaneous melanoma - A population-based estimate
H Tsao et al.
ARCHIVES OF DERMATOLOGY (2003)
High frequency of BRAF mutations in nevi
PM Pollock et al.
NATURE GENETICS (2003)
PTEN expression in normal skin, acquired melanocytic nevi, and cutaneous melanoma
H Tsao et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2003)
PTEN/MMACl expression in melanoma resection specimens
M Deichmann et al.
BRITISH JOURNAL OF CANCER (2002)
Mutations of the BRAF gene in human cancer
H Davies et al.
NATURE (2002)
Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma
DC Whiteman et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Quantitative in situ evaluation of telomeres in fluorescence in situ hybridization-processed sections of cutaneous melanocytic lesions and correlation with telomerase activity
C Miracco et al.
BRITISH JOURNAL OF DERMATOLOGY (2002)
Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma
A Demunter et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2001)
Correlation between clinical atypia and histologic dysplasia in acquired melanocytic nevi
G Annessi et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2001)
Assessment of clonality in melanocytic nevi
P Hui et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2001)
Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases
GM Kraehn et al.
BRITISH JOURNAL OF CANCER (2001)
Epigenetic PTEN silencing in malignant melanomas without PTEN mutation
XP Zhou et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features
BC Bastian et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Telomerase activity in melanocytic lesions -: A potential marker of tumor biology
P Rudolph et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Melanocytic nevus with pregnancy-related changes in size accompanied by apoptosis of nevus cells: A case report
HJ Lee et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2000)
Frequency and characteristics of enlarging common melanocytic nevi
H Kittler et al.
ARCHIVES OF DERMATOLOGY (2000)
TIA-1 positive tumor-infiltrating lymphocytes in nevi and melanomas
S Lyle et al.
MODERN PATHOLOGY (2000)
Genotype/phenotype and penetrance studies in melanoma families with germline CDKN2A mutations
JAN Bishop et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2000)