Journal
CANCER INVESTIGATION
Volume 36, Issue 8, Pages 458-473Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/07357907.2018.1517362
Keywords
Supportive care & Symptom control; Outcomes Research; Breast Cancers
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Funding
- Sydney Research
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Purpose: To ascertain how change in upper body lymphedema is assessed and understand how clinically significant change is determined. Method: A systematic search of the literature resulted in 55 eligible studies for analysis. Results: A range of assessment methods, measurement protocols, and outcomes were used in the literature. Of the 21 studies in which thresholds for change were set a priori, 20 different thresholds were reported. Conclusion: How data was measured, analysed and reported was inconsistent across studies. Consensus on a core outcome set with standardised assessment protocols and reporting; and investigation into empirically based minimum important differences (MID) is needed.
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