Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 43, Pages 8015-8019Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob02268b
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Funding
- Natural Science Foundation of Shandong Province for Outstanding Young Scholars [ZR2016JL012, ZR2018MB009]
- National Natural Science Foundation of China [21302110, 21302109]
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An efficient and eco-friendly protocol for the KI-catalyzed regioselective sulfenylation of 4-anilinocoumarins with Bunte salts was established. The reaction worked smoothly under metal-free conditions and afforded a wide range of sulfenylated 4-anilinocoumarins with potential bioactivity in moderate to excellent yields. This method would expand the still limited scope of synthesis methods for C-S bond formation using Bunte salts.
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