Journal
DATA IN BRIEF
Volume 16, Issue -, Pages 521-526Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.dib.2017.11.040
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- Taiwan Ministry of Health and Welfare Clinical Trial and Research Center of Excellence [MOHW105-TDU-B-212-133019]
- China Medical University Hospital [DMR-106-136]
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In association with the published article Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy (Huang et al., 2017) [1], this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart. (C) 2018 Published by Elsevier Inc.
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