Journal
EPILEPSY & BEHAVIOR CASE REPORTS
Volume 10, Issue -, Pages 61-64Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ebcr.2018.05.002
Keywords
Ketogenic diet; Ketosis; Ketoacidosis; Status epilepticus; Refractory status epilepticus; Super-refractory status epilepticus; Sodium-glucose cotransporter 2 inhibitor; Epilepsy; Seizure; Pentobarbital
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Background: A ketogenic diet (KD) may have a role in treating patients in super-refractory status epilepticus (SRSE). Sodium-glucose cotransporter 2 (SGLT2) inhibitors have a risk of ketoacidosis that could facilitate induction of KD. Case summary: A 42-year-old with a history of drug resistant epilepsy developed SRSE requiting several pharmacological interventions during her hospital course including the initiation of KD that failed. SGLT2 inhibitor therapy was initiated in a successful attempt to augment ketone production. Conclusion: SGLT2 inhibitors may have a therapeutic value in SRSE patients who cannot achieve ketosis with KD alone. (C) 2018 The Authors. Published by Elsevier Inc.
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