Journal
OBSTETRICS AND GYNECOLOGY
Volume 130, Issue 1, Pages 51-63Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/AOG.0000000000002106
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Funding
- NCRR NIH HHS [P51 RR000167] Funding Source: Medline
- NICHD NIH HHS [R21 HD063031, R01 HD072077, R21 HD061896] Funding Source: Medline
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Since ancient times, cervical assessment for predicting timing of delivery has relied primarily on digital (subjective) assessment of dilatation, softening, and length. To date, transvaginal ultrasound cervical length is the only one of these parameters that meets criteria for a biomarker; no objective, quantitative measure of cervical dilatation or softening has gained clinical acceptance. This review discusses how the cervix has been assessed from ancient times to the present day and how a precision medicine approach could improve understanding of not only the cervix, but also parturition in general.
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