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Volume 18, Issue -, Pages 348-359Publisher
ELSEVIER
DOI: 10.1016/j.dib.2018.02.081
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Funding
- Russian Science Foundation [14-25-00013]
- Russian Science Foundation [17-25-00005] Funding Source: Russian Science Foundation
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Guanine-rich DNA/RNA fragments can fold into G-quadruplexes (G4s) - non-canonical four-strand secondary structures. The article contains data on quadruplex interaction with human proteins. Binding of three topologically different G4 structures to more than 9000 human proteins was analyzed. Physicochemical methods were used to verify the results.The dataset was generated to identify the protein targets for DNA quadruplex structures for the purpose of better understanding the role of the structures in gene expression regulation. Presented data include functional interpretation of obtained gene lists, visualized with Cytoscape. (C) 2018 The Authors. Published by Elsevier Inc.
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