Journal
NUTRITION
Volume 34, Issue -, Pages 55-57Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nut.2016.09.010
Keywords
Creatine; Bioenergetics; Guanidinoacetic acid; SLC6 A6; SLC6 A13
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Funding
- Serbian Ministry of Education, Science and Technological Development [175037]
- Provincial Secretariat for Science and Technological Development [114-451-710/2016-03]
- Faculty of Sport and Physical Education, University of Novi Sad
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Tissues with high-energy output, such as the brain and skeletal muscle, suffer the most from impaired or depleted energy levels, with innovative nutritional approaches needed to effectively tackle metabolic deficits in bioenergetics. Here, we highlight the role of guanidinoacetic acid in the control and provision of cellular energy by its interaction with cellular transporters for taurine (SLC6 A6) and gamma-aminobutyric acid (SLC6 A13), previously dismissed as untargetable carriers by other bioenergetics therapeutics. (C) 2016 Elsevier Inc. All rights reserved.
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