Related references
Note: Only part of the references are listed.Managing the sequence-specificity of antisense oligonucleotides in drug discovery
Peter H. Hagedorn et al.
NUCLEIC ACIDS RESEARCH (2017)
Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H
Jayakanth Kankanala et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function
Walt F. Lima et al.
NUCLEIC ACIDS RESEARCH (2016)
tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes
Todd M. Lowe et al.
NUCLEIC ACIDS RESEARCH (2016)
The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA
Timothy A. Vickers et al.
NUCLEIC ACIDS RESEARCH (2015)
Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication
J. Bradley Holmes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Sequence motifs associated with hepatotoxicity of locked nucleic acid-modified antisense oligonucleotides
Andrew D. Burdick et al.
NUCLEIC ACIDS RESEARCH (2014)
A Kinetic Model Explains Why Shorter and Less Affine Enzyme-recruiting Oligonucleotides Can Be More Potent
Lykke Pedersen et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2014)
Hidden specificity in an apparently nonspecific RNA-binding protein
Ulf-Peter Guenther et al.
NATURE (2013)
Complexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradation
Mikalai Lapkouski et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Molecular mimicry of human tRNALys anti-codon domain by HIV-1 RNA genome facilitates tRNA primer annealing
Christopher P. Jones et al.
RNA (2013)
Hepatotoxic Potential of Therapeutic Oligonucleotides Can Be Predicted from Their Sequence and Modification Pattern
Peter H. Hagedorn et al.
NUCLEIC ACID THERAPEUTICS (2013)
Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
Martin A. M. Reijns et al.
CELL (2012)
Assessing unintended hybridization-induced biological effects of oligonucleotides
Morten Lindow et al.
NATURE BIOTECHNOLOGY (2012)
Viral evolution in deep time: lentiviruses and mammals
Robert J. Gifford
TRENDS IN GENETICS (2012)
Global quantification of mammalian gene expression control
Bjoern Schwanhaeusser et al.
NATURE (2011)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
Formation of the tRNALys packaging complex in HIV-1
Lawrence Kleiman et al.
FEBS LETTERS (2010)
Multiple Nucleotide Preferences Determine Cleavage-Site Recognition by the HIV-1 and M-MuLV RNases H
Sharon J. Schultz et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Ribonuclease H: the enzymes in eukaryotes
Susana M. Cerritelli et al.
FEBS JOURNAL (2009)
Ribonuclease H: properties, substrate specificity and roles in retroviral reverse transcription
James J. Champoux et al.
FEBS JOURNAL (2009)
Preferred Sequences within a Defined Cleavage Window Specify DNA 3′ End-directed Cleavages by Retroviral RNases H
Sharon J. Schultz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Structure of human RNase h1 complexed with an RNA/DNA hybrid: Insight into HIV reverse transcription
Marcin Nowotny et al.
MOLECULAR CELL (2007)
Nucleotides within the anticodon stem are important for optimal use of tRNALys,3 as the primer for HIV-1 reverse transcription
Anna McCulley et al.
VIROLOGY (2007)
Tighter binding of HIV reverse transcriptase to RNA-DNA versus DNA-DNA results mostly from interactions in the polymerase domain and requires just a small stretch of RNA-DNA
William P. Bohlayer et al.
BIOCHEMISTRY (2006)
Sequence, distance, and accessibility are determinants of 5′-end-directed cleavages by retroviral RNases H
SJ Schultz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Eukaryotic RNases H1 act processively by interactions through the duplex RNA-binding domain
SA Gaidamakov et al.
NUCLEIC ACIDS RESEARCH (2005)
Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs
HJ Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Forced selection of a human immunodeficiency virus type 1 variant that uses a non-self tRNA primer for reverse transcription: Involvement of viral RNA sequences and the reverse transcriptase enzyme
TEM Abbink et al.
JOURNAL OF VIROLOGY (2004)
'Binding, bending and bonding': polypurine tract-primed initiation of plus-strand DNA synthesis in human immunodeficiency virus
JW Rausch et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
The tRNALys packaging complex in HIV-1
L Kleiman et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Recognition of internal cleavage sites by retroviral RNases H
SJ Schultz et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice
SM Cerritelli et al.
MOLECULAR CELL (2003)
Selection for thermodynamically stable DNA tetraloops using temperature gradient gel electrophoresis reveals four motifs: d(cGNNAg), d(cGNABg), d(cCNNGg), and d(gCNNGc)
M Nakano et al.
BIOCHEMISTRY (2002)
Switching the in vitro tRNA usage of HIV-1 by simultaneous adaptation of the PBS and PAS
N Beerens et al.
RNA (2002)
The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides
ALMA ten Asbroek et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Initiation of HIV-1 reverse transcription is regulated by a primer activation signal
N Beerens et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Phylogenetic analysis of ribonuclease H domains suggests a late, chimeric origin of LTR retrotransposable elements and retroviruses
HS Malik et al.
GENOME RESEARCH (2001)
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA
SG Sarafianos et al.
EMBO JOURNAL (2001)
Essential regions of the tRNA primer required for HIV-1 infectivity
Q Yu et al.
NUCLEIC ACIDS RESEARCH (2000)
Unique progressive cleavage mechanism of HIV reverse transcriptase RNase H
M Wisniewski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Effects of RNA secondary structure on cellular antisense activity
TA Vickers et al.
NUCLEIC ACIDS RESEARCH (2000)
Share Paper
