Journal
DATA IN BRIEF
Volume 16, Issue -, Pages 65-70Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.dib.2017.10.068
Keywords
Wnt; Beta-catenin; Regeneration; Spinal cord; Zebrafish
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Funding
- Deutsche Forschungsgemeinschaft [WE5736/1-1]
- BBSRC [BB/L021498/1]
- BBSRC [BB/L021498/1] Funding Source: UKRI
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This data article contains descriptive and experimental data on spinal cord regeneration in larval zebrafish and its dependence on Wnt/beta-catenin signaling. Analyzing spread of intraspinally injected fluorescent dextran showed that anatomical continuity is rapidly restored after complete spinal cord transection. Pharmacological interference with Wnt/beta-catenin signaling (IWR-1) impaired restoration of spinal continuity. For further details and experimental findings please refer to the research article by Wehner et al. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish (Wehner et al., 2017) [1]. (C) 2017 The Authors. Published by Elsevier Inc.
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