Related references
Note: Only part of the references are listed.Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer
U. Bharadwaj et al.
ONCOGENE (2015)
Neuregulin Autocrine Signaling Promotes Self-Renewal of Breast Tumor-Initiating Cells by Triggering HER2/HER3 Activation
Cleo Yi-Fang Lee et al.
CANCER RESEARCH (2014)
STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Efficacious
Paola Maycotte et al.
CANCER RESEARCH (2014)
Artemin, a Member of the Glial Cell Line-derived Neurotrophic Factor Family of Ligands, Is HER2-regulated and Mediates Acquired Trastuzumab Resistance by Promoting Cancer Stem Cell-like Behavior in Mammary Carcinoma Cells
Keshuo Ding et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Salinomycin Suppresses LRP6 Expression and Inhibits Both Wnt/β-catenin and mTORC1 Signaling in Breast and Prostate Cancer Cells
Wenyan Lu et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2014)
Adjuvant Endocrine Therapy for Women With Hormone Receptor-Positive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline Focused Update
Harold J. Burstein et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation
Ying Sun et al.
MOLECULAR CANCER (2014)
Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis
Patricia Cortazar et al.
LANCET (2014)
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): survival outcomes of a randomised, open-label, multicentre, phase 3 trial and their association with pathological complete response
Evandro de Azambuja et al.
LANCET ONCOLOGY (2014)
Clonal evolution in breast cancer revealed by single nucleus genome sequencing
Yong Wang et al.
NATURE (2014)
Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
Allison S. Cleary et al.
NATURE (2014)
A time-and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies
Chun-Chao Wang et al.
NATURE CELL BIOLOGY (2014)
An integrin β3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition
Laetitia Seguin et al.
NATURE CELL BIOLOGY (2014)
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression
Janna K. Mouw et al.
NATURE MEDICINE (2014)
Targeting Unique Metabolic Properties of Breast Tumor Initiating Cells
Weiguo Feng et al.
STEM CELLS (2014)
Chloroquine Eliminates Cancer Stem Cells Through Deregulation of Jak2 and DNMT1
Dong Soon Choi et al.
STEM CELLS (2014)
Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells
Hira Lal Goel et al.
CELL REPORTS (2014)
Wnt-Responsive Cancer Stem Cells Are Located Close to Distorted Blood Vessels and Not in Hypoxic Regions in a p53-Null Mouse Model of Human Breast Cancer
Tegy J. Vadakkan et al.
STEM CELLS TRANSLATIONAL MEDICINE (2014)
Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts
Suling Liu et al.
STEM CELL REPORTS (2014)
Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA)
A. Schneeweiss et al.
ANNALS OF ONCOLOGY (2013)
Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers
Hazem Ghebeh et al.
BMC CANCER (2013)
Breast cancer subtypes: response to radiotherapy and potential radiosensitisation
F. E. Langlands et al.
BRITISH JOURNAL OF RADIOLOGY (2013)
Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells
Ming Qiu et al.
CANCER LETTERS (2013)
Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors
Anindita Chakrabarty et al.
CANCER RESEARCH (2013)
FOXC2 Expression Links Epithelial-Mesenchymal Transition and Stem Cell Properties in Breast Cancer
Brett G. Hollier et al.
CANCER RESEARCH (2013)
Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics
Ming Luo et al.
CANCER RESEARCH (2013)
HER2 Drives Luminal Breast Cancer Stem Cells in the Absence of HER2 Amplification: Implications for Efficacy of Adjuvant Trastuzumab
Suthinee Ithimakin et al.
CANCER RESEARCH (2013)
Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
Christine L. Chaffer et al.
CELL (2013)
Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells
Seog-Young Kim et al.
CELLULAR SIGNALLING (2013)
Current Status of Anti-Human Epidermal Growth Factor Receptor 2 Therapies: Predicting and Overcoming Herceptin Resistance
Alice Chung et al.
CLINICAL BREAST CANCER (2013)
Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms
Jagdeep K. Singh et al.
CLINICAL CANCER RESEARCH (2013)
Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Jerry Usary et al.
CLINICAL CANCER RESEARCH (2013)
Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
Alfonso Quintas-Cardama et al.
CLINICAL CANCER RESEARCH (2013)
Preclinical and Clinical Studies of Gamma Secretase Inhibitors with Docetaxel on Human Breast Tumors
Anne F. Schott et al.
CLINICAL CANCER RESEARCH (2013)
Cell Plasticity and Heterogeneity in Cancer
Nemanja D. Marjanovic et al.
CLINICAL CHEMISTRY (2013)
GLI1 regulates a novel neuropilin-2/61 integrin based autocrine pathway that contributes to breast cancer initiation
Hira Lal Goel et al.
EMBO MOLECULAR MEDICINE (2013)
Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses
Diana J. Azzam et al.
EMBO MOLECULAR MEDICINE (2013)
The Wnt-β-catenin pathway represses let-7 microRNA expression through transactivation of Lin28 to augment breast cancer stem cell expansion
Wang-Yu Cai et al.
JOURNAL OF CELL SCIENCE (2013)
TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer
Neil E. Bhola et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies
Ariella B. Hanker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Three-dimensional vasculature reconstruction of tumour microenvironment via local clustering and classification
Yanqiao Zhu et al.
INTERFACE FOCUS (2013)
TGF-β-Id1 Signaling Opposes Twist1 and Promotes Metastatic Colonization via a Mesenchymal-to-Epithelial Transition
Marko Stankic et al.
CELL REPORTS (2013)
Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling
Hannah Harrison et al.
BREAST CANCER RESEARCH (2013)
Phase lb pilot study to evaluate reparixin in combination with chemotherapy with weekly paclitaxel in patients with HER-2 negative metastatic breast cancer (MBC)
A. F. Schott et al.
CANCER RESEARCH (2012)
Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland
Renee van Amerongen et al.
CELL STEM CELL (2012)
Cancer Stem Cells: Current Status and Evolving Complexities
Jane E. Visvader et al.
CELL STEM CELL (2012)
Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland
Elena Garcia-Zaragoza et al.
DEVELOPMENTAL BIOLOGY (2012)
Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis
Venkata Lokesh Battula et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+Breast Cancer by Expanding the Cancer Stem Cell Population
Hasan Korkaya et al.
MOLECULAR CELL (2012)
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
Luca Gianni et al.
LANCET ONCOLOGY (2012)
Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer
M. Kondratyev et al.
ONCOGENE (2012)
CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling
P-K Lo et al.
ONCOGENE (2012)
Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch
James M. Haughian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells
Jason I. Herschkowitz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Cancer stem cells and epithelial-mesenchymal transition: Concepts and molecular links
Christina Scheel et al.
SEMINARS IN CANCER BIOLOGY (2012)
Integrins as therapeutic targets
Simon L. Goodman et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Characterization of mammary cancer stem cells in the MMTV-PyMT mouse model
Jun Ma et al.
TUMOR BIOLOGY (2012)
MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem Cells
Suling Liu et al.
PLOS GENETICS (2012)
Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells through Cytokine Networks
Suling Liu et al.
CANCER RESEARCH (2011)
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
Piyush B. Gupta et al.
CELL (2011)
Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast
Christina Scheel et al.
CELL (2011)
Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened
Adriana P. Visbal et al.
DEVELOPMENTAL BIOLOGY (2011)
ABCG2 is associated with HER-2 Expression, lymph node metastasis and clinical stage in breast invasive ductal carcinoma
Lei Xiang et al.
DIAGNOSTIC PATHOLOGY (2011)
Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study
Tobias Baeuerle et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
Brian D. Lehmann et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors
Lauren L. C. Marotta et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Clinical Notice for American Society of Clinical Oncology-College of American Pathologists Guideline Recommendations on ER/PgR and HER2 Testing in Breast Cancer
M. Elizabeth Hammond et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype
Sara Ricardo et al.
JOURNAL OF CLINICAL PATHOLOGY (2011)
Deconstructing the molecular portraits of breast cancer
Aleix Prat et al.
MOLECULAR ONCOLOGY (2011)
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
Dimitrios Iliopoulos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells
Desheng Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
Christine L. Chaffer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells is Primarily Due to Isoform ALDH1A3 and Its Expression is Predictive of Metastasis
Paola Marcato et al.
STEM CELLS (2011)
Ablation of Breast Cancer Stem Cells with Radiation
Steven P. Zielske et al.
TRANSLATIONAL ONCOLOGY (2011)
Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
Madhuri Kakarala et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Regulation of Breast Cancer Stem Cell Activity by Signaling through the Notch4 Receptor
Hannah Harrison et al.
CANCER RESEARCH (2010)
CD44posCD49fhiCD133/2hi Defines Xenograft-Initiating Cells in Estrogen Receptor-Negative Breast Cancer
Matthew J. Meyer et al.
CANCER RESEARCH (2010)
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content
Salvatore Pece et al.
CELL (2010)
Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture
Yi Arial Zeng et al.
CELL STEM CELL (2010)
Heterogeneity for Stem Cell-Related Markers According to Tumor Subtype and Histologic Stage in Breast Cancer
So Yeon Park et al.
CLINICAL CANCER RESEARCH (2010)
CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
Christophe Ginestier et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Issues and updates: evaluating estrogen receptor-α, progesterone receptor, and HER2 in breast cancer
D. Craig Allred
MODERN PATHOLOGY (2010)
Doxorubicin in Combination with a Small TGFβ Inhibitor: A Potential Novel Therapy for Metastatic Breast Cancer in Mouse Models
Abhik Bandyopadhyay et al.
PLOS ONE (2010)
Selective targeting of radiation-resistant tumor-initiating cells
Mei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling
Christine M. Fillmore et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
Huiping Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Thermal Enhancement with Optically Activated Gold Nanoshells Sensitizes Breast Cancer Stem Cells to Radiation Therapy
Rachel L. Atkinson et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
Aleix Prat et al.
BREAST CANCER RESEARCH (2010)
Mammary Epithelial-Specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/Progenitor Cells
Ming Luo et al.
CANCER RESEARCH (2009)
Immunoselection of Breast and Ovarian Cancer Cells with Trastuzumab and Natural Killer Cells: Selective Escape of CD44high/CD24low/HER2low Breast Cancer Stem Cells
Florian Reim et al.
CANCER RESEARCH (2009)
Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
Emmanuelle Charafe-Jauffret et al.
CANCER RESEARCH (2009)
Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
Piyush B. Gupta et al.
CELL (2009)
The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells
Angelo Cicalese et al.
CELL (2009)
MicroRNAs: Target Recognition and Regulatory Functions
David P. Bartel
CELL (2009)
Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells
Christine Mayr et al.
CELL (2009)
Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
Yohei Shimono et al.
CELL (2009)
Tumor-Initiating Cells of HER2-Positive Carcinoma Cell Lines Express the Highest Oncoprotein Levels and Are Sensitive to Trastuzumab
Alessandra Magnifico et al.
CLINICAL CANCER RESEARCH (2009)
Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells
Qing-Quan Li et al.
CLINICAL CANCER RESEARCH (2009)
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
Bryan T. MacDonald et al.
DEVELOPMENTAL CELL (2009)
High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability
Alysha K. Croker et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation
Xuejun Xu et al.
PLOS ONE (2009)
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
Chad J. Creighton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Regulation of Mammary Stem/Progenitor Cells by PTEN/Akt/β-Catenin Signaling
Hasan Korkaya et al.
PLOS BIOLOGY (2009)
Dynamic regulation of CD24 and the invasive, CD44(pos)CD24(neg) phenotype in breast cancer cell lines
Matthew J. Meyer et al.
BREAST CANCER RESEARCH (2009)
β1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
Catherine C. Park et al.
CANCER RESEARCH (2008)
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer
Mei Zhang et al.
CANCER RESEARCH (2008)
The mammary progenitor marker CD61/β3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis
Francois Vaillant et al.
CANCER RESEARCH (2008)
Cross-talk between Notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches
Paola Rizzo et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
The let-7 microRNA reduces tumor growth in mouse models of lung cancer
Aurora Esquela-Kerscher et al.
CELL CYCLE (2008)
Breast cancer subtype approximated by estrogen receptor, progesterone receptor, and HER-2 is associated with local and distant recurrence after breast-conserving therapy
Paul L. Nguyen et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
IL-8 as antibody therapeutic target in inflammatory diseases: Reduction of clinical activity in palmoplantar pustulosis
Lone Skov et al.
JOURNAL OF IMMUNOLOGY (2008)
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
Xiaoxian Li et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)
Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFκB and cooperating with Stat3
Josema Torres et al.
NATURE CELL BIOLOGY (2008)
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
H. Korkaya et al.
ONCOGENE (2008)
Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors
Robert W. Cho et al.
STEM CELLS (2008)
ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients
Tanja Fehm et al.
BREAST CANCER RESEARCH (2008)
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
Christine M. Fillmore et al.
BREAST CANCER RESEARCH (2008)
Iet-7 regulates self renewal and tumorigenicity of breast cancer cells
Fengyan Yu et al.
CELL (2007)
CXC chemokines located in the 4q21 region are up-regulated in breast cancer
Ivan Bieche et al.
ENDOCRINE-RELATED CANCER (2007)
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
Christophe Ginestier et al.
CELL STEM CELL (2007)
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance
Jiangbing Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Transforming growth factor-β can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model
Binwu Tang et al.
CANCER RESEARCH (2007)
Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-Induced mammary tumors
Jeff C. Liu et al.
CANCER RESEARCH (2007)
Quantitative measurement of epidermal growth factor receptor is a negative predictive factor for tamoxifen response in hormone receptor -: Positive premenopausal breast cancer
Jennifer M. Giltnane et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Novel cell culture technique for primary ductal carcinoma in situ: Role of notch and epidermal growth factor receptor signaling pathways
Gillian Farnie et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia
Ricardo C. Moraes et al.
DEVELOPMENT (2007)
Molecular definition of breast tumor heterogeneity
Michail Shipitsin et al.
CANCER CELL (2007)
Wnt/β-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line
Mercy S. Chen et al.
JOURNAL OF CELL SCIENCE (2007)
WNT/β-catenin mediates radiation resistance of mouse mammary progenitor cells
Wendy A. Woodward et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
Jason I. Herschkowitz et al.
GENOME BIOLOGY (2007)
The response of CD24-/low/CD44+ breast cancer-initiating cells to radiation
Tiffany M. Phillips et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer
Suleiman Massarweh et al.
CANCER RESEARCH (2006)
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
Suling Liu et al.
CANCER RESEARCH (2006)
Benefit from adjuvant tamoxifen therapy in primary breast cancer patients according oestrogen receptor, progesterone receptor, EGF receptor and HER2 status
M Dowsett et al.
ANNALS OF ONCOLOGY (2006)
β1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo
CC Park et al.
CANCER RESEARCH (2006)
CD44(+)/CD24(-) breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis
Carol Sheridan et al.
BREAST CANCER RESEARCH (2006)
Notch signalling: a simple pathway becomes complex
Sarah J. Bray
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Silencing of microRNAs in vivo with 'antagomirs'
J Krützfeldt et al.
NATURE (2005)
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival:: an overview of the randomised trials
O Abe et al.
LANCET (2005)
Opinion - Migrating cancer stem cells - an integrated concept of malignant tumour progression
T Brabletz et al.
NATURE REVIEWS CANCER (2005)
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
L Patrawala et al.
CANCER RESEARCH (2005)
Overview of the impact of conventional systemic therapies on breast cancer
A Howell et al.
ENDOCRINE-RELATED CANCER (2005)
Growth factor signalling and response to endocrine therapy: the Royal Marsden Experience
M Dowsett et al.
ENDOCRINE-RELATED CANCER (2005)
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival:: an overview of the randomised trials
O Abe et al.
LANCET (2005)
Impact of metastatic estrogen receptor and progesterone receptor status on survival
EE Lower et al.
BREAST CANCER RESEARCH AND TREATMENT (2005)
TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem
D James et al.
DEVELOPMENT (2005)
The stats of cancer - New molecular targets come of age
H Yu et al.
NATURE REVIEWS CANCER (2004)
A distinct side population of cells with high drug efflux capacity in human tumor cells
C Hirschmann-Jax et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Expression of luminal and basal cytokeratins in human breast carcinoma
DMA El-Rehim et al.
JOURNAL OF PATHOLOGY (2004)
Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
G Dontu et al.
BREAST CANCER RESEARCH (2004)
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
Y Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling
R Clarke et al.
ONCOGENE (2003)
Expression of MRP1, LRP and Pgp in breast carcinoma patients treated with preoperative chemotherapy
M Rudas et al.
BREAST CANCER RESEARCH AND TREATMENT (2003)
Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis
PM Siegel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
G Dontu et al.
GENES & DEVELOPMENT (2003)
Prospective identification of tumorigenic breast cancer cells
M Al-Hajj et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells
JM Knowlden et al.
ENDOCRINOLOGY (2003)
Aromatase inhibitors for breast cancer: Lessons from the laboratory
SRD Johnston et al.
NATURE REVIEWS CANCER (2003)
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases
GN Naumov et al.
BREAST CANCER RESEARCH AND TREATMENT (2003)
Stemness: Transcriptional profiling of embryonic and adult stem cells
M Ramalho-Santos et al.
SCIENCE (2002)
WNT signals are required for the initiation of hair follicle development
T Andl et al.
DEVELOPMENTAL CELL (2002)
Hedgehog signaling in animal development: paradigms and principles
PW Ingham et al.
GENES & DEVELOPMENT (2001)
Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance
NJ Turton et al.
ONCOGENE (2001)
Molecular portraits of human breast tumours
CM Perou et al.
NATURE (2000)
Association of STATs with relatives and friends
M Chatterjee-Kishore et al.
TRENDS IN CELL BIOLOGY (2000)