Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 100, Pages 14108-14111Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc08570f
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Funding
- National Science Foundation of China [21525105, 21471164, 21778079, 21771042]
- 973 Program [2015CB856301]
- Ministry of Education of China [IRT-17R111]
- China Postdoctoral Science Foundation [2018M630988]
- Fundamental Research Funds for the Central Universities
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Iridium complexes were used as a mitochondria-targeting agent to modify the surface of a photothermogenic nanozyme Fe3O4 nanoparticles (Ir@Fe3O4 NPs). Upon NIR irradiation, Ir@Fe3O4 NPs increase the localized temperature to 42 degrees C which accelerates the catalysis of OH production from H2O2 resulting in excellent mild photothermal therapy.
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