Journal
NEW JOURNAL OF CHEMISTRY
Volume 41, Issue 4, Pages 1714-1722Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6nj01120a
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- CSIR, New Delhi
- UGC, New Delhi
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A new class of triazoloferrocenyl conjugates (1, 2 and 3) was obtained by copper(I) catalyzed click chemistry, specifically the alkyne azide cycloaddition (CuAAC) of bis(beta-hydroxyl) arylalkyneether with suitable ferrocenyl azides. The synthesized bis(b-hydroxyl) arylether linked ferrocenyl conjugates 1, 2 and 3 exhibit antifungal activity against fungal pathogens, viz. Candida albicans, Candida glabrata and Candida crusi, comparable to that of amphotericin B and also show excellent anticancer activity against MCF-7 cell lines.
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