4.6 Article

Hydrogel degradation triggered by pH for the smart release of antibiotics to combat bacterial infection

Journal

NEW JOURNAL OF CHEMISTRY
Volume 41, Issue 2, Pages 432-436

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6nj03260e

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Funding

  1. National Natural Science Foundation of China [51401149, 51273152, 51473129, 51503160]
  2. National Science-technology Support Program of China [2015BAE01B01]
  3. Innovation Group Project of Science and Technology Department of Hubei province [2015CFA028]
  4. Excellent Young and Middle-aged Innovation Team Project of Education Department of Hubei province [T201408]

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Here we developed a hydrogel that could be triggered by a change in pH to degrade and smartly release antibiotics to combat a bacterial infection; use of this hydrogel could reduce the inappropriate and disproportionate use of antibiotics.

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