Journal
NEW JOURNAL OF CHEMISTRY
Volume 41, Issue 10, Pages 3723-3731Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7nj00379j
Keywords
-
Categories
Funding
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico [CNPq 480719/2012-8, 474797/2013-9, PVE 401193/2014-4, PQ-SR CNPq 302613/2013-7]
- FAPEMIG [01/2014]
- Programa Pesquisador Mineiro
- CAPES
- FAPERJ
- CAPES/PROCAD
- PAPES/Fiocruz
Ask authors/readers for more resources
Phenazinic ligands and Ru(II)-based complexes were synthesized from natural products lapachol and lawsone and evaluated against T. cruzi, the etiological agent of Chagas disease. These new ruthenium compounds could provide promising trypanocidal drugs. Besides synthesis and trypanocidal activity, this paper reports photophysical features and computational details of the compounds. The fluorescent trypanocidal substances are promising derivatives for further studies aiming to find molecules active against parasites associated with neglected diseases.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available