Journal
NEW JOURNAL OF CHEMISTRY
Volume 41, Issue 13, Pages 5513-5520Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7nj00738h
Keywords
-
Categories
Funding
- Science and Engineering Research Board, Department of Science and Technology, New Delhi, India [YSS/2014/000546]
Ask authors/readers for more resources
A series of luminescent ruthenium(II) polypyridyl complexes containing an extended aromatic moiety derived from triptycene and 1,10-phenanthroline were synthesized and their photophysical, theoretical, and biological properties were investigated. These complexes rapidly condense DNA into nano-aggregates at room temperature. The DNA interactions and DNA condensation properties of these complexes were investigated by absorption and emission spectroscopy, electrophoretic mobility assay, and atomic force microscopy. Their DNA cleavage inactivity and low toxicity of the complexes satisfy the requirements of a good non-viral gene delivery vector.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available