Journal
NEUROSURGERY
Volume 81, Issue 3, Pages 397-415Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1093/neuros/nyx103
Keywords
Brain tumors; Diffusion MRI; Diffusion tensor imaging; fMRI; Neuroimaging; Perfusion MRI; Proton magnetic resonance spectroscopy
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Funding
- NIH [5 T32 EB001631-12]
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Neuroimaging plays an ever evolving role in the diagnosis, treatment planning, and post-therapy assessment of brain tumors. This review provides an overview of current magnetic resonance imaging (MRI) methods routinely employed in the care of the brain tumor patient. Specifically, we focus on advanced techniques including diffusion, perfusion, spectroscopy, tractography, and functional MRI as they pertain to noninvasive characterization of brain tumors and pretreatment evaluation. The utility of both structural and physiological MRI in the post-therapeutic brain evaluation is also reviewed with special attention to the challenges presented by pseudoprogression and pseudoresponse.
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