Journal
JOURNAL OF BREAST CANCER
Volume 21, Issue 4, Pages 343-353Publisher
KOREAN BREAST CANCER SOC
DOI: 10.4048/jbc.2018.21.e47
Keywords
Breast neoplasms; Immunology; Immunotherapy; Vaccines
Categories
Funding
- Yildiz Technical University, Istanbul, Turkey [FYL-2017-3202, 2015-07-04-KAP04]
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Cancer is the leading cause of death worldwide. In developed as well as developing countries, breast cancer is the most common cancer found among women. Currently, treatment of breast cancer consists mainly of surgery, chemotherapy, hormone therapy, and radiotherapy. In recent years, because of increased understanding of the therapeutic potential of immunotherapy in cancer prevention, cancer vaccines have gained importance. Here, we review various immunotherapeutic breast cancer vaccines including peptide-based vaccines, whole tumor cell vaccines, gene-based vaccines, and dendritic cell vaccines. We also discuss novel nanotechnology-based approaches to improving breast cancer vaccine efficiency.
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