4.8 Editorial Material

Testing the Amyloid Hypothesis with a Humanized AD Mouse Model

Journal

NEURON
Volume 93, Issue 5, Pages 987-989

Publisher

CELL PRESS
DOI: 10.1016/j.neuron.2017.02.044

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Funding

  1. VA [978286, 5I01RX002133-02] Funding Source: Federal RePORTER
  2. RRD VA [I01 RX002133] Funding Source: Medline

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In this issue of Neuron, Espuny-Camacho et al. (2017) generate a humanized Alzheimer's disease (AD) model that reveals species-specific vulnerability of human neurons to AD pathology. This model provides key insights for disease mechanism and therapeutic discovery for AD.

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