3.8 Review

Recent Trifluoromethylation Reactions. (A Mini Review)

Journal

ORIENTAL JOURNAL OF CHEMISTRY
Volume 34, Issue 6, Pages 2708-2715

Publisher

ORIENTAL SCIENTIFIC PUBL CO
DOI: 10.13005/ojc/340603

Keywords

Trifluoromethylation; Photocatalyst process; Togni's reagent; Umemoto's reagent; Langlois' reagent; diastereoselectivity

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This review highlights recent improvement in trifluoromethylene functionalization processes with CF3 reagents, includes: Togni's, Umemoto's, CF3SO2Cl, CF3I, Yagupol'skii-Umemoto, TMSCF3, Langlois (CF3SO2Na) and clarifies the several designing to result the corresponding trifluoromethylated products. In this article, the selective trifluoromethylation reactions with Togni's reagents and their analogs are detailed, which work transition metals or photoactivated Ru or Ir catalysts as single electron giver to yield CF3 radical intermediate species. This issue is to introduce a draft of diverse reports, presenting the modern reaction collect and mechanics produced during the past five years. This task is demanded by the key protocol connected with the trifluoromethylation reactions, designing to sustain researchers a straight forward understanding of such reactions and to award information for further implements.

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