4.1 Article

Can 8 months of daily tDCS application slow the cognitive decline in Alzheimer's disease? A case study

Journal

NEUROCASE
Volume 23, Issue 2, Pages 146-148

Publisher

ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/13554794.2017.1325911

Keywords

Alzheimer's disease; transcranial direct current stimulation; tDCS; neuromodulation

Funding

  1. University of Tromso, North Norway

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This case study presents a patient with early-onset Alzheimer`s disease, who applied transcranial direct current stimulation (tDCS) daily for 8 consecutive months. This was a much higher frequency than previous tDCS studies. Neuropsychological assessments were conducted before the first tDCS session, after 5 months and after 8 months. After 8 months, the patient's immediate recall improved with 39%, whereas delayed recall improved 23%. Overall, the results revealed that patient's cognitive functions were stabilized. There may be slight possibility that tDCS could slow the cognitive decline in Alzheimer`s disease. This should be investigated in clinical trials.

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