Journal
NEUROBIOLOGY OF LEARNING AND MEMORY
Volume 142, Issue -, Pages 79-84Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.nlm.2017.02.018
Keywords
Anisomycin; alpha-amanitin; Muscimol; Novelty; Retrieval
Funding
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq, Brazil)
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES, Brazil)
- CNPq Junior Post-Doctoral Fellowship
- CAPES
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Reconsolidation restabilizes memory after reactivation. Previously, we reported that the hippocampus is engaged in object recognition memory reconsolidation to allow incorporation of new information into the original engram. Here we show that BDNF is sufficient for this process, and that blockade of BDNF function in dorsal CA(1) impairs updating of the reactivated recognition memory trace. (C) 2017 Elsevier Inc. All rights reserved.
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