Journal
CRISPR JOURNAL
Volume 1, Issue 1, Pages 34-46Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/crispr.2018.29007.fyu
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Genome editing with engineered nucleases, a powerful tool for understanding biological function and revealing causality, was built in a joint effort by academia and industry in 1994-2010. Use of CRISPR-Cas9 is the most recent (2013-), and facile, implementation of the resulting editing toolbox. Principles and methods of genome editing from the pre-CRISPR era remain relevant and continue to be useful.
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