3.8 Article

INVESTIGATION OF REACTION OF VARIOUS THIOPHENE BASED KNOEVENAGEL ADDUCTS WITH ACETOACETANILIDE

Journal

CHEMICAL PROBLEMS
Volume -, Issue 3, Pages 337-342

Publisher

INST CATALYST & INORGANIC CHEMISTRY
DOI: 10.32737/2221-8688-2018-3-337-342

Keywords

thiophene; acrylonitrile; acetoacetanilide; pyran; NMR

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The reaction of Michael addition interaction of 3-phenyl-2-(thiophene-2-carbonyl)acrylonitrile, 2-(thiophene-2-carbonyl)-3-(p-tolyl)acrylonitrile, 3-(4-methoxyphenyl)-2-(thiophene-2-carbonyl)acrylonitril, as well as 3-pyridinyl-2-(thiophene-2-carbonyl)acrylonitrile with acetoacetanilide made it possible to produce substituted hexanones and 3,4-dihydro- 2H-pyrane derivatives. Structures of synthesized compounds were acknowledged by NMR and X-Ray structural analysis.

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