4.1 Article Data Paper

Data highlighting the expression of two miR-132/212 target genes-Sirt1 and Pten-after chronic stress

Journal

DATA IN BRIEF
Volume 21, Issue -, Pages 2323-2329

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.dib.2018.11.042

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Funding

  1. National Institutes of Health [MH103361, N5066345, N5091302]
  2. National Science Foundation [1354612]
  3. Direct For Biological Sciences
  4. Division Of Integrative Organismal Systems [1354612] Funding Source: National Science Foundation

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The data presented here are related to our research article entitled miR-132/212 is induced by stress and its dysregulation triggers anxiety -related behavior (Aten et al., 2018). In this article, we utilize immunofluorescent techniques to examine the protein level expression of two microRNA-132/212 target genes, Sirt1 and Pten, in miR-132 transgenic and miR-132/212 conditional knockout (cKO) mouse lines. Additionally, using immunohistochemistry, we detail the expression profile of Sirt1 and Pten in the hippocampus and amygdala of WT mice after a 15 day chronic restraint stress paradigm. (C) 2018 The Authors. Published by Elsevier Inc.

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