Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 24, Issue 6, Pages 503-506Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.3412
Keywords
-
Ask authors/readers for more resources
The DNA-adenine modification N-6-methyladenine (6mA), initially thought to be mainly restricted to prokaryotes and certain unicellular eukaryotes, has recently been found in metazoans. Proposed functions vary from gene activation to transposon suppression. However, since most metazoan genomes possess 5-methylcytosine (5mC) as a dominant epigenetic mark, it raises the question of why 6mA is required. This Perspective summarizes the latest discoveries and suggests potential functional roles for 6mA in metazoan genomes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available