Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 24, Issue 1, Pages 13-+Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.3353
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Loss of function of the CFTR anion channel leads to cystic fibrosis, the most common inherited condition in humans of European origin. A recently reported structure for CFTR at 3.7-angstrom resolution reveals an unexpected 'lasso' domain and provides new insights into channel function in healthy individuals and in people with cystic fibrosis.
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