Related references
Note: Only part of the references are listed.Selectivity determinants of GPCR-G-protein binding
Tilman Flock et al.
NATURE (2017)
Mechanisms of Autoantibody-Induced Pathology
Ralf J. Ludwig et al.
FRONTIERS IN IMMUNOLOGY (2017)
Autoantibodies against β1-adrenoceptor induce blood glucose enhancement and insulin insufficient via T lymphocytes
Yulin Gong et al.
IMMUNOLOGIC RESEARCH (2016)
TNF biology, pathogenic mechanisms and emerging therapeutic strategies
George D. Kalliolias et al.
NATURE REVIEWS RHEUMATOLOGY (2016)
Aptamer BC007 for neutralization of pathogenic autoantibodies directed against G-protein coupled receptors: A vision of future treatment of patients with cardiomyopathies and positivity for those autoantibodies
Gerd Wallukat et al.
ATHEROSCLEROSIS (2016)
Antibodies against angiotensin II type 1 receptor (AT1R) and endothelin receptor type A (ETAR) in systemic sclerosis (SSc)-response
Gabriela Riemekasten et al.
AUTOIMMUNITY REVIEWS (2016)
Vascular hypothesis revisited: Role of stimulating antibodies against angiotensin and endothelin receptors in the pathogenesis of systemic sclerosis
Otavio Cabral-Marques et al.
AUTOIMMUNITY REVIEWS (2016)
Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome
Madlen Loebel et al.
BRAIN BEHAVIOR AND IMMUNITY (2016)
Monocytic Angiotensin and Endothelin Receptor Imbalance Modulate Secretion of the Profibrotic Chemokine Ligand 18
Judith Rademacher et al.
JOURNAL OF RHEUMATOLOGY (2016)
Localization and function of the renal calcium-sensing receptor
Daniela Riccardi et al.
NATURE REVIEWS NEPHROLOGY (2016)
Engineering therapeutic antibodies targeting G-protein-coupled receptors
Migyeong Jo et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2016)
Gastrointestinal manifestations of systemic sclerosis
Andrew B. Shreiner et al.
JOURNAL OF SCLERODERMA AND RELATED DISORDERS (2016)
Chemokines, their receptors and human disease: the good, the bad and the itchy
Vanessa L. Bryant et al.
IMMUNOLOGY AND CELL BIOLOGY (2015)
Molecular Mechanisms Underlying β-Adrenergic Receptor-Mediated Cross-Talk between Sympathetic Neurons and Immune Cells
Dianne Lorton et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Functional Autoantibodies in Systemic Sclerosis Pathogenesis
Angela Kill et al.
CURRENT RHEUMATOLOGY REPORTS (2015)
Anti-Endothelin Receptor Type A Autoantibodies in Systemic Lupus Erythematosus-Associated Pulmonary Arterial Hypertension
Li Guo et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Adrenergic regulation of innate immunity: a review
Angela Scanzano et al.
FRONTIERS IN PHARMACOLOGY (2015)
Vascular Receptor Autoantibodies in Pulmonary Arterial Hypertension Associated with Systemic Sclerosis
Mike O. Becker et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
Tubulin, actin and heterotrimeric G proteins: Coordination of signaling and structure
Jeffrey M. Schappi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)
A novel luminescence-based method for the detection of functionally active antibodies to muscarinic acetylcholine receptors of the M3 type (mAchR3) in patients' sera
B. Preuss et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2014)
Serum CCL18 is predictive for lung disease progression and mortality in systemic sclerosis
Jonas Schupp et al.
EUROPEAN RESPIRATORY JOURNAL (2014)
Muscarinic acetylcholine receptors: novel opportunities for drug development
Andrew C. Kruse et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Angiotensin receptor type 1 and endothelin receptor type A on immune cells mediate migration and the expression of IL-8 and CCL18 when stimulated by autoantibodies from systemic sclerosis patients
Jeannine Guenther et al.
ARTHRITIS RESEARCH & THERAPY (2014)
Autoantibodies to angiotensin and endothelin receptors in systemic sclerosis induce cellular and systemic events associated with disease pathogenesis
Angela Kill et al.
ARTHRITIS RESEARCH & THERAPY (2014)
The role of the paracrine/autocrine mediator endothelin-1 in regulation of cardiac contractility and growth
Faye M. Drawnel et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
The role of angiotensin II type 1 receptor-activating antibodies in patients with lupus nephritis
J. Xiong et al.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2013)
Calcium-Sensing Receptor Autoantibodies and Idiopathic Hypoparathyroidism
Neeraj Tomar et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
First Clinical Experience With TRV027: Pharmacokinetics and Pharmacodynamics in Healthy Volunteers
David G. Soergel et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Identification of human CCR8 as a CCL18 receptor
Sabina A. Islam et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1
Yutaka Koyama et al.
JOURNAL OF NEUROINFLAMMATION (2013)
The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility
Kyungpyo Park et al.
MOLECULAR IMMUNOLOGY (2013)
Molecular signatures of G-protein-coupled receptors
A. J. Venkatakrishnan et al.
NATURE (2013)
Agonistic anti-ICAM-1 antibodies in scleroderma: Activation of endothelial pro-inflammatory cascades
Sabine I. Wolf et al.
VASCULAR PHARMACOLOGY (2013)
The activity of CCL18 is principally mediated through interaction with glycosaminoglycans
Sonja Krohn et al.
FRONTIERS IN IMMUNOLOGY (2013)
Drug-like actions of autoantibodies against receptors of the autonomous nervous system and their impact on human heart function
L. R. Herda et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
TRV120027, a Novel β-Arrestin Biased Ligand at the Angiotensin II Type I Receptor, Unloads the Heart and Maintains Renal Function When Added to Furosemide in Experimental Heart Failure
Guido Boerrigter et al.
CIRCULATION-HEART FAILURE (2012)
β1-adrenergic receptor autoantibodies from heart failure patients enhanced TNF-α secretion in RAW264.7 macrophages in a largely PKA-dependent fashion
Yunhui Du et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2012)
Role of anti-ß1 adrenergic antibodies from patients with periodontitis in cardiac dysfunction
Marcela Segovia et al.
JOURNAL OF ORAL PATHOLOGY & MEDICINE (2012)
Deciphering actin cytoskeletal function in the contractile vascular smooth muscle cell
Rina Yamin et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
β1-Adrenoceptor Autoantibodies from DCM Patients Enhance the Proliferation of T Lymphocytes through the β1-AR/cAMP/PKA and p38 MAPK Pathways
Yunhui Du et al.
PLOS ONE (2012)
Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts
Xu Shi-wen et al.
RHEUMATOLOGY (2012)
Endothelin-1 contributes to increased NFATc3 activation by chronic hypoxia in pulmonary arteries
Sergio de Frutos et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Peptide-based ELISAs are not sensitive and specific enough to detect muscarinic receptor type 3 autoantibodies in serum from patients with Sjogren's syndrome
N. Roescher et al.
ANNALS OF THE RHEUMATIC DISEASES (2011)
Involvement of functional autoantibodies against vascular receptors in systemic sclerosis
Gabriela Riemekasten et al.
ANNALS OF THE RHEUMATIC DISEASES (2011)
Antibodies Interfering With the Type 3 Muscarinic Receptor Pathway Inhibit Gastrointestinal Motility and Cholinergic Neurotransmission in Sjogren's Syndrome
Kyungpyo Park et al.
ARTHRITIS AND RHEUMATISM (2011)
A family tree of vertebrate chemokine receptors for a unified nomenclature
Hisayuki Nomiyama et al.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2011)
Long-term active immunization with a synthetic peptide corresponding to the second extracellular loop of β1-adrenoceptor induces both morphological and functional cardiomyopathic changes in rats
Lin Zuo et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2011)
Immunoadsorption (IAS) for systemic lupus erythematosus
G. H. Stummvoll
LUPUS (2011)
Autoimmunity against the β2 adrenergic receptor and muscarinic-2 receptor in complex regional pain syndrome
Danielle Kohr et al.
PAIN (2011)
First report of anti-calcium-sensing receptor antibodies in a patient with Sjogren's syndrome and primary hypoparathyroidism
Helen E. Harris et al.
RHEUMATOLOGY (2011)
New epitopes and function of anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sjogren's syndrome
H. Tsuboi et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
Teaching old receptors new tricks: biasing seven-transmembrane receptors
Sudarshan Rajagopal et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Muscarinic-3 acetylcholine receptor autoantibody in patients with systemic sclerosis: contribution to severe gastrointestinal tract dysmotility
Y. Kawaguchi et al.
ANNALS OF THE RHEUMATIC DISEASES (2009)
Autoantibodies against the platelet-derived growth factor receptor in scleroderma: comment on the articles by Classen et al and Loizos et al
Armando Gabrielli et al.
ARTHRITIS AND RHEUMATISM (2009)
CXCR3+CD4+T Cells Are Enriched in Inflamed Kidneys and Urine and Provide a New Biomarker for Acute Nephritis Flares in Systemic Lupus Erythematosus Patients
P. Enghard et al.
ARTHRITIS AND RHEUMATISM (2009)
The proadhesive phenotype of systemic sclerosis skin promotes myeloid cell adhesion via ICAM-1 and VCAM-1
Bradley J. Rabquer et al.
RHEUMATOLOGY (2009)
Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans
I. Wessler et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Physiologic properties and regulation of the actin cytoskeleton in vascular smooth muscle
Dale D. Tang et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2008)
Role of muscarinic receptors in the regulation of immune and inflammatory responses
Seddigheh Razani-Boroujerdi et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
Long-term effects of bosentan on quality of life, survival, safety and tolerability in pulmonary arterial hypertension related to connective tissue diseases
C. P. Denton et al.
ANNALS OF THE RHEUMATIC DISEASES (2008)
Functional autoantibodies, a new paradigm in autoimmunity?
Norbert Gleicher et al.
AUTOIMMUNITY REVIEWS (2007)
Anti-β1-adrenergic receptor autoantibodies are potent stimulators of the ERK1/2 pathway in cardiac cells
Antonio S. Tutor et al.
CARDIOVASCULAR RESEARCH (2007)
Hypoparathyroidism in systemic lupus erythematosus
Hassene Attout et al.
JOINT BONE SPINE (2007)
Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation
Marco Scarselli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
M-2 and M-3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: findings obtained with muscarinic-receptor knockout mouse
Tadayoshi Takeuchi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Physiology of the autonomic nervous system
Laurie Kelly McCorry
AMERICAN JOURNAL OF PHARMACEUTICAL EDUCATION (2007)
The relevance of the IgG subclass of autoantibodies for blister induction in autoimmune bullous skin diseases
Cassian Sitaru et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2007)
Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
Juergen Wess et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Roles of M2 and M3 muscarinic receptors in cholinergic nerve-induced contractions in mouse ileum studied with receptor knockout mice
T. Unno et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Opinion - How many drug targets are there?
John P. Overington et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Association of systemic and thyroid autoimmune diseases
E Biró et al.
CLINICAL RHEUMATOLOGY (2006)
Antibodies against human cytomegalovirus in the pathogenesis of systemic sclerosis: A gene array approach
C Lunardi et al.
PLOS MEDICINE (2006)
Molecular mechanisms of beta(2)-adrenergic receptor function, response, and regulation
M Johnson
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Clinical associations of autoantibodies to human muscarinic acetylcholine receptor 3213-228 in primary Sjogren's syndrome
L Kovács et al.
RHEUMATOLOGY (2005)
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection
D Dragun et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Antibodies to TSH-receptor in thyroid autoimmune disease interact with monoclonal antibodies whose epitopes are broadly distributed on the receptor
WB Minich et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2004)
Endothelin-1 promotes phosphorylation of CREB transcription factor in primary cultures of neonatal rat cardiac myocytes:: implications for the regulation of c-jun expression
JG Harrison et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
Activating antibodies to the calcium-sensing receptor in two patients with autoimmune hypoparathyroidism
O Kifor et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Effects of endothelin ETA receptor antagonism on granulocyte and lymphocyte accumulation in LPS-induced inflammation
ALF Sampaio et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors
Y Kawaguchi et al.
ARTHRITIS AND RHEUMATISM (2004)
Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney
M Ruiz-Ortega et al.
KIDNEY INTERNATIONAL (2002)
Antibody-mediated gastrointestinal dysmotility in scleroderma
F Goldblatt et al.
GASTROENTEROLOGY (2002)
Extracellular signal-regulated kinase plays an essential role in endothelin-1-induced homotypic adhesion of human neutrophil granulocytes
L Jozsef et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
The balance of Th1/Th2 cytokines in rheumatoid arthritis
H Schulze-Koops et al.
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2001)
Angiotensin II induces migration and Pyk2/paxillin phosphorylation of human monocytes
U Kintscher et al.
HYPERTENSION (2001)
Angiotensin II activates nuclear transcription factor κB through AT1 and AT2 in vascular smooth muscle cells -: Molecular mechanisms
M Ruiz-Ortega et al.
CIRCULATION RESEARCH (2000)
Angiotensin III increases MCP-1 and activates NF-κB and AP-1 in cultured mesangial and mononuclear cells
M Ruiz-Ortega et al.
KIDNEY INTERNATIONAL (2000)
Endothelin-1 induces interleukin-6 release via activation of the transcription factor NF-κB in human vascular smooth muscle cells
M Browatzki et al.
BASIC RESEARCH IN CARDIOLOGY (2000)