Related references
Note: Only part of the references are listed.Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis
Marjolein Garsen et al.
AMERICAN JOURNAL OF PATHOLOGY (2016)
Vascular Growth Factors and Glomerular Disease
Christina S. Bartlett et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 78 (2016)
Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy
Margien G. S. Boels et al.
DIABETES (2016)
Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx
Marjolein Garsen et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
Cathepsin L is crucial for the development of early experimental diabetic nephropathy
Marjolein Garsen et al.
KIDNEY INTERNATIONAL (2016)
Autophagy in kidney disease and aging: lessons from rodent models
Olivia Lenoir et al.
KIDNEY INTERNATIONAL (2016)
Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria
Marjolein Garsen et al.
PLOS ONE (2016)
Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis
Marina Weissmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury
Valentina Masola et al.
PLOS ONE (2016)
Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy
Anna Shteingauz et al.
CANCER RESEARCH (2015)
Modulation of the binding of basic fibroblast growth factor and heparanase activity by purified λ-carrageenan oligosaccharides
Ting-Ting Niu et al.
CARBOHYDRATE POLYMERS (2015)
Heparanase activates the syndecan-syntenin-ALIX exosome pathway
Bart Roucourt et al.
CELL RESEARCH (2015)
The cell biology of renal filtration
Rizaldy P. Scott et al.
JOURNAL OF CELL BIOLOGY (2015)
Vitamin D attenuates proteinuria by inhibition of heparanase expression in the podocyte
Marjolein Garsen et al.
JOURNAL OF PATHOLOGY (2015)
Perlecan inhibits autophagy to maintain muscle homeostasis in mouse soleus muscle
Liang Ning et al.
MATRIX BIOLOGY (2015)
Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease
M. Teresa Grande et al.
NATURE MEDICINE (2015)
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
Sara Lovisa et al.
NATURE MEDICINE (2015)
The glycocalyx-linking albuminuria with renal and cardiovascular disease
Ton J. Rabelink et al.
NATURE REVIEWS NEPHROLOGY (2015)
Structural characterization of human heparanase reveals insights into substrate recognition
Liang Wu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Structural characterization of human heparanase reveals insights into substrate recognition
Liang Wu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
The effect of CCR2 inhibitor CCX140-B on residual albuminuria in patients with type 2 diabetes and nephropathy: a randomised trial
Dick de Zeeuw et al.
LANCET DIABETES & ENDOCRINOLOGY (2015)
Shed Syndecan-1 Translocates to the Nucleus of Cells Delivering Growth Factors and Inhibiting Histone Acetylation A NOVEL MECHANISM OF TUMOR-HOST CROSS-TALK
Mark D. Stewart et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Upregulated Expression of Heparanase in the Vitreous of Patients With Proliferative Diabetic Retinopathy Originates From Activated Endothelial Cells and Leukocytes
Ahmed M. Abu El-Asrar et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
A microscopic view on the renal endothelial glycocalyx
Martijn J. C. Dane et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2015)
Heparanase induces inflammatory cell recruitment in vivo by promoting adhesion to vascular endothelium
Rebecca Lever et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)
Demystifying Heparan Sulfate-Protein Interactions
Ding Xu et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)
1H NMR spectroscopic studies establish that heparanase is a retaining glycosidase
Jennifer C. Wilson et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Processing of heparanase is mediated by syndecan-1 cytoplasmic domain and involves syntenin and α-actinin
Anna Shteingauz et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Role of Heparanase-Driven Inflammatory Cascade in Pathogenesis of Diabetic Nephropathy
Rachel Goldberg et al.
DIABETES (2014)
Heparan Sulfate Containing Unsubstituted Glucosamine Residues BIOSYNTHESIS AND HEPARANASE-INHIBITORY ACTIVITY
Satomi Nadanaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
β-Arrestin-1 Drives Endothelin-1-Mediated Podocyte Activation and Sustains Renal Injury
Simona Buelli et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)
Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis
Angelique L. W. M. M. Rops et al.
KIDNEY INTERNATIONAL (2014)
Heparan sulfate in the nucleus and its control of cellular functions
Mark D. Stewart et al.
MATRIX BIOLOGY (2014)
The Protective Role of Fucosylated Chondroitin Sulfate, a Distinct Glycosaminoglycan, in a Murine Model of Streptozotocin-Induced Diabetic Nephropathy
Conrado L. R. Gomes et al.
PLOS ONE (2014)
Soluble Heparan Sulfate Fragments Generated by Heparanase Trigger the Release of Pro-Inflammatory Cytokines through TLR-4
Katharine J. Goode et al.
PLOS ONE (2014)
Macrophage Activation by Heparanase Is Mediated by TLR-2 and TLR-4 and Associates With Plaque Progression
Miry Blich et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)
Heparanase in inflammation and inflammation-associated cancer
Amichay Meirovitz et al.
FEBS JOURNAL (2013)
Multi-faceted substrate specificity of heparanase
Sherket B. Peterson et al.
MATRIX BIOLOGY (2013)
Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues
Edward Hammond et al.
FEBS OPEN BIO (2013)
Heparanase and autoimmune diabetes
Charmaine J. Simeonovic et al.
FRONTIERS IN IMMUNOLOGY (2013)
Heparanase mediates renal dysfunction during early sepsis in mice
Melissa I. Lygizos et al.
PHYSIOLOGICAL REPORTS (2013)
Fatty Acid-Induced Nuclear Translocation of Heparanase Uncouples Glucose Metabolism in Endothelial Cells
Fang Wang et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation
Todd V. Brennan et al.
BLOOD (2012)
Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice
Natali Gil et al.
DIABETES (2012)
Computational analyses of the catalytic and heparin-binding sites and their interactions with glycosaminoglycans in glycoside hydrolase family 79 endo-β-d-glucuronidase (heparanase)
Neha S. Gandhi et al.
GLYCOBIOLOGY (2012)
Heparanase and Syndecan-1 Interplay Orchestrates Fibroblast Growth Factor-2-induced Epithelial-Mesenchymal Transition in Renal Tubular Cells
Valentina Masola et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Endothelial Heparan Sulfate 6-O-Sulfation Levels Regulate Angiogenic Responses of Endothelial Cells to Fibroblast Growth Factor 2 and Vascular Endothelial Growth Factor
Cristina Ferreras et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes
Andrew F. Ziolkowski et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Sulodexide Fails to Demonstrate Renoprotection in Overt Type 2 Diabetic Nephropathy
David K. Packham et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)
Urinary heparanase activity in patients with Type 1 and Type 2 diabetes
Angelique L. W. M. M. Rops et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2012)
Elevated Urine Heparanase Levels Are Associated with Proteinuria and Decreased Renal Allograft Function
Itay Shafat et al.
PLOS ONE (2012)
Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial
Edmund J. Lewis et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2011)
SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis
Joseph P. Ritchie et al.
CLINICAL CANCER RESEARCH (2011)
Reactive oxygen species mediate high glucose-induced heparanase-1 production and heparan sulphate proteoglycan degradation in human and rat endothelial cells: a potential role in the pathogenesis of atherosclerosis
G. Rao et al.
DIABETOLOGIA (2011)
Heparanase-mediated Loss of Nuclear Syndecan-1 Enhances Histone Acetyltransferase (HAT) Activity to Promote Expression of Genes That Drive an Aggressive Tumor Phenotype
Anurag Purushothaman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival
Suma Yaddanapudi et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice
Immanuel Lerner et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and combined therapy in patients with micro- and macroalbuminuria and other cardiovascular risk factors: a systematic review of randomized controlled trials
Ausilia Maione et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2011)
Heparanase Levels Are Elevated in the Urine and Plasma of Type 2 Diabetes Patients and Associate with Blood Glucose Levels
Itay Shafat et al.
PLOS ONE (2011)
Anti-Proteinuric Effect of Sulodexide in Immunoglobulin A Nephropathy
Kitae Bang et al.
YONSEI MEDICAL JOURNAL (2011)
Heparan Sulfate Proteoglycans
Stephane Sarrazin et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils
Sara Massena et al.
BLOOD (2010)
Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction
Alessandro Fantin et al.
BLOOD (2010)
Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus
L. N. Broekhuizen et al.
DIABETOLOGIA (2010)
Heparanase 2 Interacts with Heparan Sulfate with High Affinity and Inhibits Heparanase Activity
Flonia Levy-Adam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Heparanase in Primary Human Osteoblasts
Paul N. Smith et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2010)
Proteinuria: an enzymatic disease of the podocyte?
Peter Mundel et al.
KIDNEY INTERNATIONAL (2010)
Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial
Dick de Zeeuw et al.
LANCET (2010)
Induction of Heparanase-1 Expression by Mutant B-Raf Kinase: Role of GA Binding Protein in Heparanase-1 Promoter Activation
Geetha Rao et al.
NEOPLASIA (2010)
Vitamin D, Proteinuria, Diabetic Nephropathy, and Progression of CKD
Rajiv Agarwal
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Abnormal Angiogenesis in Diabetic Nephropathy
Takahiko Nakagawa et al.
DIABETES (2009)
Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species
Mabel J. van den Hoven et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)
Heparanase prevents the development of type 1 diabetes in non-obese diabetic mice by regulating T-cell activation and cytokines production
Menachem Bitan et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2008)
Inhibition of histone acetyltransferase by glycosaminoglycans
Jo Ann Buczek-Thomas et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo
Shafaat A. Rabbani
NEOPLASIA (2008)
Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation
Robert J. Wood et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Heparanase induces a differential loss of heparan sulphate domains in overt diabetic nephropathy
T. J. M. Wijnhoven et al.
DIABETOLOGIA (2008)
Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate
Martha L. Escobar Galvis et al.
NATURE CHEMICAL BIOLOGY (2007)
Expression of glomerular heparan sulphate domains in murine and human lupus nephritis
Angelique L. Rops et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2007)
Heparan sulphate proteoglycans fine-tune mammalian physiology
Joseph R. Bishop et al.
NATURE (2007)
Estradiol induces heparanase-1 expression and heparan sulphate proteoglycan degradation in human endometrium
Xiulong Xu et al.
HUMAN REPRODUCTION (2007)
Translocation of heparanase into nucleus results in cell differentiation
Tetsuji Nobuhisa et al.
CANCER SCIENCE (2007)
New approaches to the treatment of dense deposit disease
Richard J. H. Smith et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
Heparanase in glomerular diseases
M. J. van den Hoven et al.
KIDNEY INTERNATIONAL (2007)
Increased expression of heparanase in overt diabetic nephropathy
M. J. van den Hoven et al.
KIDNEY INTERNATIONAL (2006)
Induction of glomerular heparanase expression in rats with Adriamycin nephropathy is regulated by reactive oxygen species and the renin-angiotensin system
Andrea Kramer et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Tumor suppressor p53 regulates heparanase gene expression
L. Baraz et al.
ONCOGENE (2006)
Role of endothelial heparanase in delayed-type hypersensitivity
E Edovitsky et al.
BLOOD (2006)
An ELISA method for the detection and quantification of human heparanase
I Shafat et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Heparanase induces vascular endothelial growth factor expression: Correlation with p38 phosphorylation levels and Src activation
A Zetser et al.
CANCER RESEARCH (2006)
Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation
KR Taylor et al.
FASEB JOURNAL (2006)
The role of heparan sulphate in inflammation
Christopher R. Parish
NATURE REVIEWS IMMUNOLOGY (2006)
Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells
AM de Mestre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Promoter CpG hypomethylation and transcription factor EGR1 hyperactivate heparanase expression in bladder cancer
T Ogishima et al.
ONCOGENE (2005)
Cellular uptake of mammalian heparanase precursor involves low density lipoprotein receptor-related proteins, mannose 6-phosphate receptors, and heparan sulfate Proteoglycans
V Vreys et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Heparanase-1 gene expression and regulation by high glucose in renal epithelial cells - A potential role in the pathogenesis of proteinuria in diabetic patients
JB Maxhimer et al.
DIABETES (2005)
Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase
F Levy-Adam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cell surface localization of heparanase on macrophages regulates degradation of extracellular matrix heparan sulfate
N Sasaki et al.
JOURNAL OF IMMUNOLOGY (2004)
Heparan sulfate proteoglycans in glomerular inflammation
ALWMM Rops et al.
KIDNEY INTERNATIONAL (2004)
Heparanase is involved in the pathogenesis of proteinuria as a result of glomerulonephritis
V Levidiotis et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)
A synthetic heparanase inhibitor reduces proteinuria in passive Heymann nephritis
V Levidiotis et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)
Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans
S Gingis-Velitski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Inflammatory cytokines and fatty acids regulate endothelial cell heparanase expression
GP Chen et al.
BIOCHEMISTRY (2004)
Processing and activation of latent heparanase occurs in lysosomes
A Zetser et al.
JOURNAL OF CELL SCIENCE (2004)
Regulation of inducible heparanase gene transcription in activated T cells by early growth response 1
AM de Mestre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of promoter methylation in regulation of the mammalian heparanase gene
PJ Shteper et al.
ONCOGENE (2003)
Endothelial inflammation: the role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate
NM Carter et al.
JOURNAL OF CELL SCIENCE (2003)
Trans-activation of heparanase promoter by ETS transcription factors
WC Lu et al.
ONCOGENE (2003)
Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis - Hierarchical sulfate groups with differential effects and the essential target disulfated trisaccharide sequence
Y Okada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Selective modulation of the secretion of proteinases and their inhibitors by growth factors in cultured differentiated podocytes
K Asanuma et al.
KIDNEY INTERNATIONAL (2002)
Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type I and type 2 diabetic patients:: The Di.NAS randomized trial
G Gambaro et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
Cloning and characterization of the human heparanase-1 (HPR1) gene promoter -: Role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activity
P Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Urinary levels of monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8), and renal injuries in patients with type 2 diabetic nephropathy
K Tashiro et al.
JOURNAL OF CLINICAL LABORATORY ANALYSIS (2002)
Increased expression of heparanase in puromycin aminonucleoside nephrosis
V Levidiotis et al.
KIDNEY INTERNATIONAL (2001)
Update in podocyte biology
K Endlich et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2001)
A specific structural alteration in the heparan sulphate of human glomerular basement membrane in diabetes
ASB Edge et al.
DIABETOLOGIA (2000)
Expression of agrin, dystroglycan, and utrophin in normal renal tissue and in experimental glomerulopathies
CJI Raats et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)