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Renoprotective effects of GLP1R agonists and SGLT2 inhibitors

Journal

NATURE REVIEWS NEPHROLOGY
Volume 13, Issue 12, Pages 728-729

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nrneph.2017.140

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Funding

  1. Boehringer Ingelheim

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New data from the LEADER trial show that the glucagon-like peptide 1 receptor agonist liraglutide protects against diabetic nephropathy in patients with type 2 diabetes mellitus. The renoprotective efficacy of liraglutide is not, however, as great as that reported for the sodium-glucose cotransporter 2 inhibitor emplagiflozin in the EMPA-REG OUTCOME trial.

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