Related references
Note: Only part of the references are listed.Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation
Ivo A. Hendriks et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease
Rocio Gomez-Pastor et al.
NATURE COMMUNICATIONS (2017)
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation
Ivo A. Hendriks et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
NEDD4-mediated HSF1 degradation underlies α-synucleinopathy
Eunhee Kim et al.
HUMAN MOLECULAR GENETICS (2016)
Heat-shock factor 2 is a suppressor of prostate cancer invasion
J. K. Bjork et al.
ONCOGENE (2016)
HSF1-deficiency affects gait coordination and cerebellar calbindin levels
Marc Ingenwerth et al.
BEHAVIOURAL BRAIN RESEARCH (2016)
The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis
Han-Jou Chen et al.
BRAIN (2016)
Protein quantity-quality balance licenses growth
Kuo-Hui Su et al.
CELL CYCLE (2016)
The central role of heat shock factor 1 in synaptic fidelity and memory consolidation
Philip L. Hooper et al.
CELL STRESS & CHAPERONES (2016)
Increased occurrence of protein kinase CK2 in astrocytes in Alzheimer's disease pathology
Andrea F. N. Rosenberger et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Heat shock proteins as potential targets for protective strategies in neurodegeneration
Harm H. Kampinga et al.
LANCET NEUROLOGY (2016)
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
Vaishali Kakkar et al.
MOLECULAR CELL (2016)
HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth
Kuo-Hui Su et al.
NATURE CELL BIOLOGY (2016)
Structure of human heat-shock transcription factor 1 in complex with DNA
Tobias Neudegger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors
Alex M. Jaeger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
HSF1 Guardian of Proteostasis in Cancer
Chengkai Dai et al.
TRENDS IN CELL BIOLOGY (2016)
The transcriptional coactivator PGC1α protects against hyperthermic stress via cooperation with the heat shock factor HSF1
L. Xu et al.
CELL DEATH & DISEASE (2016)
Structure of human heat-shock transcription factor 1 in complex with DNA
Tobias Neudegger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors
Alex M. Jaeger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
IER5 generates a novel hypophosphorylated active form of HSF1 and contributes to tumorigenesis
Yoshinori Asano et al.
SCIENTIFIC REPORTS (2016)
Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1
Nikolai Hentze et al.
ELIFE (2016)
A minimal titration model of the mammalian dynamical heat shock response
Aude Sivery et al.
PHYSICAL BIOLOGY (2016)
MEK Guards Proteome Stability and Inhibits Tumor-Suppressive Amyloidogenesis via HSF1
Zijian Tang et al.
CELL (2015)
Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis
Xinran Ma et al.
CELL METABOLISM (2015)
Lysine Deacetylases Regulate the Heat Shock Response Including the Age-Associated Impairment of HSF1
Elena Zelin et al.
JOURNAL OF MOLECULAR BIOLOGY (2015)
Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation
Marek A. Budzynski et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification
Nikos Kourtis et al.
NATURE CELL BIOLOGY (2015)
Direct link between metabolic regulation and the heat-shock response through the transcriptional regulator PGC-1α
Neri Minsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity
Ke Tan et al.
NATURE COMMUNICATIONS (2015)
Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK
Siyuan Dai et al.
EMBO JOURNAL (2015)
HSF1 regulation of β-catenin in mammary cancer cells through control of HuR/elavL1 expression
S-D Chou et al.
ONCOGENE (2015)
Low neural exosomal levels of cellular survival factors in Alzheimer's disease
Edward J. Goetzl et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2015)
The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy
Ruth Scherz-Shouval et al.
CELL (2014)
Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1
Swasti Raychaudhuri et al.
CELL (2014)
Heat shock factor 2 is a stress-responsive mediator of neuronal migration defects in models of fetal alcohol syndrome
Rachid El Fatimy et al.
EMBO MOLECULAR MEDICINE (2014)
Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntingtons disease
Megha Maheshwari et al.
HUMAN MOLECULAR GENETICS (2014)
Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders
Alisia Carnemolla et al.
HUMAN MOLECULAR GENETICS (2014)
Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival
Alexandra N. Elsing et al.
JOURNAL OF CELL BIOLOGY (2014)
SIRT1 Knockdown Promotes Neural Differentiation and Attenuates the Heat Shock Response
Diana J. Liu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2014)
Hsp90 Chaperone Inhibitor 17-AAG Attenuates Aβ-Induced Synaptic Toxicity and Memory Impairment
Yaomin Chen et al.
JOURNAL OF NEUROSCIENCE (2014)
HDAC6-ubiquitin interaction controls the duration of HSF1 activation after heat shock
Lydia Pernet et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
PGC-lα mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
Valerie S. LeBleu et al.
NATURE CELL BIOLOGY (2014)
Evidence for the Role of AMPK in Regulating PGC-1 Alpha Expression and Mitochondrial Proteins in Mouse Epididymal Adipose Tissue
Zhongxiao Wan et al.
OBESITY (2014)
DECIPHERING HUMAN HEAT SHOCK TRANSCRIPTION FACTOR 1 REGULATION VIA POST-TRANSLATIONAL MODIFICATION IN YEAST
Liliana Batista-Nascimento et al.
INVESTIGATIONS IN YEAST FUNCTIONAL GENOMICS AND MOLECULAR BIOLOGY (2014)
Casein Kinase II Induced Polymerization of Soluble TDP-43 into Filaments Is Inhibited by Heat Shock Proteins
Yari Carlomagno et al.
PLOS ONE (2014)
A Direct Regulatory Interaction between Chaperonin TRiC and Stress-Responsive Transcription Factor HSF1
Daniel W. Neef et al.
CELL REPORTS (2014)
SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system
Seiji Watanabe et al.
MOLECULAR BRAIN (2014)
Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis
Nicolas Dzamko et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update
Daniel R. Ciocca et al.
ARCHIVES OF TOXICOLOGY (2013)
Increased heat shock transcription factor 1 in the cerebellum reverses the deficiency of Purkinje cells in Alzheimer's disease
Yu-Qing Jiang et al.
BRAIN RESEARCH (2013)
Englerin A Stimulates PKCθ to Inhibit Insulin Signaling and to Simultaneously Activate HSF1: Pharmacologically Induced Synthetic Lethality
Carole Sourbier et al.
CANCER CELL (2013)
Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease
Anson Pierce et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Expression of Taurine Transporter (TauT) is Modulated by Heat Shock Factor 1 (HSF1) in Motor Neurons of ALS
Min-Kyung Jung et al.
MOLECULAR NEUROBIOLOGY (2013)
Heat shock factor 1 over-expression protects against exposure of hydrophobic residues on mutant SOD1 and early mortality in a mouse model of amyotrophic lateral sclerosis
Pei-Yi Lin et al.
MOLECULAR NEURODEGENERATION (2013)
Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells
Anniina Vihervaara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State
Sandro Santagata et al.
SCIENCE (2013)
Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration
Naohide Kondo et al.
NATURE COMMUNICATIONS (2013)
Genetic Selection for Constitutively Trimerized Human HSF1 Mutants Identifies a Role for Coiled-Coil Motifs in DNA Binding
Daniel W. Neef et al.
G3-GENES GENOMES GENETICS (2013)
Suppression of protein aggregation by chaperone modification of high molecular weight complexes
John Labbadia et al.
BRAIN (2012)
HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers
Marc L. Mendillo et al.
CELL (2012)
Heat Shock Factor Hsf1 Cooperates with ErbB2 (Her2/Neu) Protein to Promote Mammary Tumorigenesis and Metastasis
Caixia Xi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis
Chengkai Dai et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Post-Translational Modification of Human Heat Shock Factors and Their Functions: A Recent Update by Proteomic Approach
Yan-Ming Xu et al.
JOURNAL OF PROTEOME RESEARCH (2012)
Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR
Vladimir L. Gabai et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
The p23 Molecular Chaperone and GCN5 Acetylase Jointly Modulate Protein-DNA Dynamics and Open Chromatin Status
Elena Zelin et al.
MOLECULAR CELL (2012)
RPA Assists HSF1 Access to Nucleosomal DNA by Recruiting Histone Chaperone FACT
Mitsuaki Fujimoto et al.
MOLECULAR CELL (2012)
mTOR Is Essential for the Proteotoxic Stress Response, HSF1 Activation and Heat Shock Protein Synthesis
Shiuh-Dih Chou et al.
PLOS ONE (2012)
Impaired Heat Shock Response in Cells Expressing Full-Length Polyglutamine-Expanded Huntingtin
Sidhartha M. Chafekar et al.
PLOS ONE (2012)
PGC-1α Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function
Taiji Tsunemi et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease
Julius Anckar et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80 (2011)
AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer
D. Grahame Hardie
BIOCHEMICAL SOCIETY TRANSACTIONS (2011)
β-Amyloid triggers ALS-associated TDP-43 pathology in AD models
Alexander M. Herman et al.
BRAIN RESEARCH (2011)
Heat Shock Transcription Factor 1 Is a Key Determinant of HCC Development by Regulating Hepatic Steatosis and Metabolic Syndrome
Xiongjie Jin et al.
CELL METABOLISM (2011)
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease
John Labbadia et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation
Toyohide Shinkawa et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases
Daniel W. Neef et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 1
Shusaku Uchida et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Deciphering Human Heat Shock Transcription Factor 1 Regulation via Post-Translational Modification in Yeast
Liliana Batista-Nascimento et al.
PLOS ONE (2011)
Morphological Changes of the Human Purkinje Cells and Deposition of Neuritic Plaques and Neurofibrillary Tangles on the Cerebellar Cortex of Alzheimer's Disease
Ioannis A. Mavroudis et al.
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2010)
Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT
Naoki Hayashida et al.
EMBO JOURNAL (2010)
The heat shock factor family and adaptation to proteotoxic stress
Mitsuaki Fujimoto et al.
FEBS JOURNAL (2010)
A Novel Mouse HSF3 Has the Potential to Activate Nonclassical Heat-Shock Genes during Heat Shock
Mitsuaki Fujimoto et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Dominant-positive HSF1 decreases alpha-synuclein level and alpha-synuclein-induced toxicity
Xu Liangliang et al.
MOLECULAR BIOLOGY REPORTS (2010)
Heat shock factors: integrators of cell stress, development and lifespan
Malin Akerfelt et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis
L. Meng et al.
ONCOGENE (2010)
Protein Kinase A Binds and Activates Heat Shock Factor 1
Ayesha Murshid et al.
PLOS ONE (2010)
Transcriptional coactivator PGC-1α promotes peroxisomal remodeling and biogenesis
Alessia Bagattin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis
Jesper V. Olsen et al.
SCIENCE SIGNALING (2010)
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
Ji Luo et al.
CELL (2009)
Deficit of heat shock transcription factor 1-heat shock 70 kDa protein 1A axis determines the cell death vulnerability in a model of spinocerebellar ataxia type 6
Li Li et al.
GENES TO CELLS (2009)
Heterotrimerization of Heat-Shock Factors 1 and 2 Provides a Transcriptional Switch in Response to Distinct Stimuli
Anton Sandqvist et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth
Y. H. Zhao et al.
ONCOGENE (2009)
Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1
Sandy D. Westerheide et al.
SCIENCE (2009)
Nuclear accumulation of polyglutamine disease proteins and neuropathology
Lauren S. Havel et al.
MOLECULAR BRAIN (2009)
Neural differentiation and the attenuated heat shock response
Jingxian Yang et al.
BRAIN RESEARCH (2008)
HSF1 as a mitotic regulator: Phosphorylation of HSF1 by Plk1 is essential for mitotic progression
Yoon-Jin Lee et al.
CANCER RESEARCH (2008)
Analysis of HSF4 Binding Regions Reveals Its Necessity for Gene Regulation during Development and Heat Shock Response in Mouse Lenses
Mitsuaki Fujimoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry
Heike Runne et al.
JOURNAL OF NEUROSCIENCE (2008)
Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis
Chengkai Dai et al.
CELL (2007)
Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors
J-N Min et al.
ONCOGENE (2007)
Demyelination, astrogliosis, and accumulation of ubiquitinated proteins, hallmarks of CNS disease in hsf1-deficient mice
Sachiko Homma et al.
JOURNAL OF NEUROSCIENCE (2007)
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration
Patrick Weydt et al.
CELL METABOLISM (2006)
Up-regulation of the clusterin gene after proteotoxic stress:: implication of HSF1-HSF2 heterocomplexes
F Loison et al.
BIOCHEMICAL JOURNAL (2006)
Regional and cellular gene expression changes in human Huntington's disease brain
A Hodges et al.
HUMAN MOLECULAR GENETICS (2006)
Inhibition of DNA binding by differential sumoylation of heat shock factors
J Anckar et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
PDSM, a motif for phosphorylation-dependent SUMO modification
V Hietakangas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models
M Fujimoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Characterization of HSFY, a novel AZFb gene on the Y chromosome with a possible role in human spermatogenesis
A Tessari et al.
MOLECULAR HUMAN REPRODUCTION (2004)
The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response
ND Trinklein et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Casein kinase II-mediated phosphorylation regulates α-synuclein/synphilin-1 interaction and inclusion body formation
G Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Activation of the Saccharomyces cerevisiae heat shock transcription factor under glucose starvation conditions by Snf1 protein kinase
JS Hahn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach
DG Hay et al.
HUMAN MOLECULAR GENETICS (2004)
HSF4 is required for normal cell growth and differentiation during mouse lens development
M Fujimoto et al.
EMBO JOURNAL (2004)
Genome-wide analysis of the biology of stress responses through heat shock transcription factor
JS Hahn et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2
F Soncin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1
V Hietakangas et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Lowered temperature set point for activation of the cellular stress response in T-lymphocytes
LQ Gothard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress
SG Ahn et al.
GENES & DEVELOPMENT (2003)
Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage
LJ Yan et al.
EMBO JOURNAL (2002)
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
PK Auluck et al.
SCIENCE (2002)
Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice
Q Li et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2002)
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1
CI Holmberg et al.
EMBO JOURNAL (2001)
Share Paper
