Related references
Note: Only part of the references are listed.撤稿声明: DNA-guided genome editing using the Natronobacterium gregoryi Argonaute (Retraction of Vol 34, Pg 768, 2016) (Publication with Expression of Concern. See vol. 35, pg. 481, 2017) (Publication with Expression of Concern. See vol. 35, pg. 481, 2017)
Feng Gao et al.
NATURE BIOTECHNOLOGY (2017)
Marker-free coselection for CRISPR-driven genome editing in human cells
Daniel Agudelo et al.
NATURE METHODS (2017)
Putting the squeeze on superconductivity
Kyle M. Shen
SCIENCE (2017)
INORGANIC CHEMISTRY Synthesis and characterization of the pentazolate anion cyclo-N5- in (N5)6(H3O)3(NH4)4Cl
Chong Zhang et al.
SCIENCE (2017)
Design of a synthetic yeast genome
Sarah M. Richardson et al.
SCIENCE (2017)
Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond
Leslie A. Mitchell et al.
SCIENCE (2017)
Perfect designer chromosome V and behavior of a ring derivative
Ze-Xiong Xie et al.
SCIENCE (2017)
No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells
Parisa Javidi-Parsijani et al.
PLOS ONE (2017)
Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins
Rolen M. Quadros et al.
GENOME BIOLOGY (2017)
A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases
Ioannis Karakikes et al.
CIRCULATION RESEARCH (2017)
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
Alexis C. Komor et al.
CELL (2017)
DESM: portal for microbial knowledge exploration systems
Adil Salhi et al.
NUCLEIC ACIDS RESEARCH (2016)
Combinatorial metabolic pathway assembly in the yeast genome with RNA-guided Cas9
Steve F. EauClaire et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2016)
Origins of Programmable Nucleases for Genome Engineering
Srinivasan Chandrasegaran et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
Keiichiro Suzuki et al.
NATURE (2016)
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
Daniel P. Dever et al.
NATURE (2016)
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
Frank Soldner et al.
NATURE (2016)
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Alexis C. Komor et al.
NATURE (2016)
Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA
Christopher D. Richardson et al.
NATURE BIOTECHNOLOGY (2016)
DSBCapture: in situ capture and sequencing of DNA breaks
Stefanie V. Lensing et al.
NATURE METHODS (2016)
Real-time selective sequencing using nanopore technology
Matthew Loose et al.
NATURE METHODS (2016)
Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases
Shengdar Q. Tsai et al.
NATURE REVIEWS GENETICS (2016)
Coming of age: ten years of next-generation sequencing technologies
Sara Goodwin et al.
NATURE REVIEWS GENETICS (2016)
Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair
Xiangjun He et al.
NUCLEIC ACIDS RESEARCH (2016)
Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array
Carl W. Fuller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Design, synthesis, and testing toward a 57-codon genome
Nili Ostrov et al.
SCIENCE (2016)
Design and synthesis of a minimal bacterial genome
Clyde A. Hutchison et al.
SCIENCE (2016)
Long-read sequence assembly of the gorilla genome
David Gordon et al.
SCIENCE (2016)
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
Keiji Nishida et al.
SCIENCE (2016)
The Genome Project-Write
Jef D. Boeke et al.
SCIENCE (2016)
Systematic mapping of functional enhancer-promoter connections with CRISPR interference
Charles P. Fulco et al.
SCIENCE (2016)
Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells
Mark A. DeWitt et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Mitochondrial Replacement Techniques: Divercence in Global Policy
Johanna Schandera et al.
TRENDS IN GENETICS (2016)
Engineering and optimising deaminase fusions for genome editing
Luhan Yang et al.
NATURE COMMUNICATIONS (2016)
CRISPR/Cas9 facilitates investigation of neural circuit disease using human iPSCs: mechanism of epilepsy caused by an SCN1A loss-of-function mutation
J. Liu et al.
TRANSLATIONAL PSYCHIATRY (2016)
被撤回的出版物: DNA-guided genome editing using the Natronobacterium gregoryi Argonaute (Retracted article. See vol. 35, pg. 797, 2017)
Feng Gao et al.
NATURE BIOTECHNOLOGY (2016)
Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells
Megan D. Hoban et al.
BLOOD (2015)
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Bernd Zetsche et al.
CELL (2015)
Oxford Nanopore sequencing, hybrid error correction, and de novo assembly of a eukaryotic genome
Sara Goodwin et al.
GENOME RESEARCH (2015)
High-Throughput Sequencing Technologies
Jason A. Reuter et al.
MOLECULAR CELL (2015)
Perspective: Embryo editing needs scrutiny
Jennifer Doudna
NATURE (2015)
Perspective: Encourage the innovators
George Church
NATURE (2015)
Sequential cancer mutations in cultured human intestinal stem cells
Jarno Drost et al.
NATURE (2015)
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
Matthew C. Canver et al.
NATURE (2015)
Recoded organisms engineered to depend on synthetic amino acids
Alexis J. Rovner et al.
NATURE (2015)
Biocontainment of genetically modified organisms by synthetic protein design
Daniel J. Mandell et al.
NATURE (2015)
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
Takeshi Maruyama et al.
NATURE BIOTECHNOLOGY (2015)
Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors
Jianbin Wang et al.
NATURE BIOTECHNOLOGY (2015)
De novo sequencing and variant calling with nanopores using PoreSeq
Tamas Szalay et al.
NATURE BIOTECHNOLOGY (2015)
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
Van Trung Chu et al.
NATURE BIOTECHNOLOGY (2015)
CRISPR germline engineering-the community speaks
Katrine S. Bosley et al.
NATURE BIOTECHNOLOGY (2015)
Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
Daesik Kim et al.
NATURE METHODS (2015)
Genomes by design
Adrian D. Haimovich et al.
NATURE REVIEWS GENETICS (2015)
High-throughput functional genomics using CRISPR-Cas9
Ophir Shalem et al.
NATURE REVIEWS GENETICS (2015)
Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing
Jordan Pinder et al.
NUCLEIC ACIDS RESEARCH (2015)
A prudent path forward for genomic engineering and germline gene modification
David Baltimore et al.
SCIENCE (2015)
Genome-wide inactivation of porcine endogenous retroviruses (PERVs)
Luhan Yang et al.
SCIENCE (2015)
Inclusion of homologous DNA in nuclease-mediated gene targeting facilitates a higher incidence of bi-allelically modified cells
Benjamin P. Beaton et al.
XENOTRANSPLANTATION (2015)
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes
Brian J. Beliveau et al.
NATURE COMMUNICATIONS (2015)
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
Benjamin S. Freedman et al.
NATURE COMMUNICATIONS (2015)
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Laura Ordovas et al.
STEM CELL REPORTS (2015)
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2015)
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
Richard L. Frock et al.
NATURE BIOTECHNOLOGY (2015)
Creating a monomeric endonuclease TALE-I-SceI with high specificity and low genotoxicity in human cells
Jianfei Lin et al.
NUCLEIC ACIDS RESEARCH (2015)
Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells
Susan M. Byrne et al.
NUCLEIC ACIDS RESEARCH (2015)
Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome
Mark C. Wallen et al.
PLOS ONE (2015)
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
Hiroshi Nishimasu et al.
CELL (2014)
Enhancing the Specificity of Recombinase-Mediated Genome Engineering through Dimer Interface Redesign
Thomas Gaj et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
DNA-guided DNA interference by a prokaryotic Argonaute
Daan C. Swarts et al.
NATURE (2014)
Dimeric CRISPR RNA-guided Fokl nucleases for highly specific genome editing
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2014)
Fusion of catalytically inactive Cas9 to Fokl nuclease improves the specificity of genome modification
John P. Guilinger et al.
NATURE BIOTECHNOLOGY (2014)
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
Gang Wang et al.
NATURE MEDICINE (2014)
Large-scale de novo DNA synthesis: technologies and applications
Sriram Kosuri et al.
NATURE METHODS (2014)
A guide to genome engineering with programmable nucleases
Hyongbum Kim et al.
NATURE REVIEWS GENETICS (2014)
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
Sandrine Boissel et al.
NUCLEIC ACIDS RESEARCH (2014)
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
Danielle Welter et al.
NUCLEIC ACIDS RESEARCH (2014)
MegaTevs: single-chain dual nucleases for efficient gene disruption
Jason M. Wolfs et al.
NUCLEIC ACIDS RESEARCH (2014)
CRISPR/Cas9-Mediated Gene Knock-Down in Post-Mitotic Neurons
Christoph Straub et al.
PLOS ONE (2014)
Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage
Gang Sheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Total Synthesis of a Functional Designer Eukaryotic Chromosome
Narayana Annaluru et al.
SCIENCE (2014)
Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
Shota Nakade et al.
NATURE COMMUNICATIONS (2014)
A Versatile Two-Step CRISPR- and RMCE-Based Strategy for Efficient Genome Engineering in Drosophila
Xu Zhang et al.
G3-GENES GENOMES GENETICS (2014)
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
Haoyi Wang et al.
CELL (2013)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients
Gerald Schwank et al.
CELL STEM CELL (2013)
Enhanced Efficiency of Human Pluripotent Stem Cell Genome Editing through Replacing TALENs with CRISPRs
Qiurong Ding et al.
CELL STEM CELL (2013)
Obligate Ligation-Gated Recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining
Marcello Maresca et al.
GENOME RESEARCH (2013)
A highly efficient site-specific integration strategy using combination of homologous recombination and the ΦC31 integrase
Hailong Ou et al.
JOURNAL OF BIOTECHNOLOGY (2013)
Targeted Gene Addition in Human Epithelial Stem Cells by Zinc-finger Nuclease-mediated Homologous Recombination
Andrea Coluccio et al.
MOLECULAR THERAPY (2013)
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali et al.
NATURE BIOTECHNOLOGY (2013)
Improved tools for the Brainbow toolbox
Dawen Cai et al.
NATURE METHODS (2013)
Generation of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast-embryonic stem cell fusion
Liangping Li et al.
NATURE PROTOCOLS (2013)
A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells
Thomas Gaj et al.
NUCLEIC ACIDS RESEARCH (2013)
Transcription activator like effector (TALE)-directed piggyBac transposition in human cells
Jesse B. Owens et al.
NUCLEIC ACIDS RESEARCH (2013)
Efficient Flp-Int HK022 dual RMCE in mammalian cells
Eugenia Voziyanova et al.
NUCLEIC ACIDS RESEARCH (2013)
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
James E. DiCarlo et al.
NUCLEIC ACIDS RESEARCH (2013)
Genomically Recoded Organisms Expand Biological Functions
Marc J. Lajoie et al.
SCIENCE (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Mutants of Cre recombinase with improved accuracy
Nikolai Eroshenko et al.
NATURE COMMUNICATIONS (2013)
The mammalian gene function resource: the international knockout mouse consortium
Allan Bradley et al.
MAMMALIAN GENOME (2012)
A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response
Britt Adamson et al.
NATURE CELL BIOLOGY (2012)
Genome-scale promoter engineering by coselection MAGE
Harris H. Wang et al.
NATURE METHODS (2012)
Chimeric TALE recombinases with programmable DNA sequence specificity
Andrew C. Mercer et al.
NUCLEIC ACIDS RESEARCH (2012)
Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases
Xavier Rios et al.
PLOS ONE (2012)
The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target
Amanda Nga-Sze Mak et al.
SCIENCE (2012)
Efficacy and Site-Specificity of Adenoviral Vector Integration Mediated by the Phage φC31 Integrase
Marc-Andre Robert et al.
HUMAN GENE THERAPY METHODS (2012)
Site-specific recombinases: from tag-and-target- to tag-and-exchange-based genomic modifications
Soeren Turan et al.
FASEB JOURNAL (2011)
Synthetic chromosome arms function in yeast and generate phenotypic diversity by design
Jessica S. Dymond et al.
NATURE (2011)
A new dawn for industrial photosynthesis
Dan E. Robertson et al.
PHOTOSYNTHESIS RESEARCH (2011)
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Ines G. Munoz et al.
NUCLEIC ACIDS RESEARCH (2011)
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Tomas Cermak et al.
NUCLEIC ACIDS RESEARCH (2011)
Crystal structures of λ exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity
Jinjin Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement
Farren J. Isaacs et al.
SCIENCE (2011)
Fate of Recombinant Adeno-Associated Viral Vector Genomes During DNA Double-Strand Break-Induced Gene Targeting in Human Cells
Katharina Gellhaus et al.
HUMAN GENE THERAPY (2010)
Dual RMCE for efficient re-engineering of mouse mutant alleles
Marco Osterwalder et al.
NATURE METHODS (2010)
Subtle gene modification in mouse ES cells: evidence for incorporation of unmodified oligonucleotides without induction of DNA damage
Marieke Aarts et al.
NUCLEIC ACIDS RESEARCH (2010)
Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome
Daniel G. Gibson et al.
SCIENCE (2010)
Programming cells by multiplex genome engineering and accelerated evolution
Harris H. Wang et al.
NATURE (2009)
A Genetic Strategy for Stochastic Gene Activation with Regulated Sparseness (STARS)
Sheng-zhi Wang et al.
PLOS ONE (2009)
Creating Bacterial Strains from Genomes That Have Been Cloned and Engineered in Yeast
Carole Lartigue et al.
SCIENCE (2009)
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
Zhucheng Chen et al.
NATURE (2008)
Selection and optimization of microbial hosts for biofuels production
Curt R. Fischer et al.
METABOLIC ENGINEERING (2008)
Group II Intron-Based Gene Targeting Reactions in Eukaryotes
Marta Mastroianni et al.
PLOS ONE (2008)
Ubiquity of biological ice nucleators in snowfall
Brent C. Christner et al.
SCIENCE (2008)
Crystal structure of a self-spliced group II intron
Navtej Toor et al.
SCIENCE (2008)
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences
Julianne Smith et al.
NUCLEIC ACIDS RESEARCH (2006)
Site-specific recombination of asymmetric lox sites mediated by a heterotetrameric Cre recombinase complex
T Saraf-Levy et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Efficient in toto targeted recombination in mouse liver by meganuclease-induced double-strand break
Agnes Gouble et al.
JOURNAL OF GENE MEDICINE (2006)
Accurate multiplex polony sequencing of an evolved bacterial genome
J Shendure et al.
SCIENCE (2005)
Refactoring bacteriophage T7
Leon Y. Chan et al.
MOLECULAR SYSTEMS BIOLOGY (2005)
Accurate multiplex gene synthesis from programmable DNA microchips
JD Tian et al.
NATURE (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Generating a synthetic genome by whole genome assembly:: φX174 bacteriophage from synthetic oligonucleotides
HO Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Constraints for zinc finger linker design as inferred from X-ray crystal structure of tandem Zif268-DNA complexes
E Peisach et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells
JC Epinat et al.
NUCLEIC ACIDS RESEARCH (2003)
Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes
Y Yang et al.
NATURE BIOTECHNOLOGY (2003)
Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles
G Testa et al.
NATURE BIOTECHNOLOGY (2003)
A highly efficient recombineering-based method for generating conditional knockout mutations
PT Liu et al.
GENOME RESEARCH (2003)
Design, activity, and structure of a highly specific artificial endonuclease
BS Chevalier et al.
MOLECULAR CELL (2002)
Directed evolution of the site specificity of Cre recombinase
SW Santoro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Alteration of Cre recombinase site specificity by substrate-linked protein evolution
F Buchholz et al.
NATURE BIOTECHNOLOGY (2001)
Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility
BS Chevalier et al.
NUCLEIC ACIDS RESEARCH (2001)
A bacterial artificial chromosome library for sequencing the complete human genome
K Osoegawa et al.
GENOME RESEARCH (2001)
Targeted gene correction by small single-stranded oligonucleotides in mammalian cells
O Igoucheva et al.
GENE THERAPY (2001)
Stimulation of homologous recombination through targeted cleavage by chimeric nucleases
M Bibikova et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Gene correction in hematopoietic progenitor cells by homologous recombination
S Hatada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Group II introns designed to insert into therapeutically relevant DNA target sites in human cells
HT Guo et al.
SCIENCE (2000)
A phage integrase directs efficient site-specific integration in human cells
AC Groth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
An efficient recombination system for chromosome engineering in Escherichia coli
DG Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Double trans-chromosomic mice:: Maintenance of two individual human chromosome fragments containing Ig heavy and κ loci and expression of fully human antibodies
K Tomizuka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Share Paper
