4.7 Editorial Material

Neonatal gut microbiota induces lung immunity against pneumonia

Journal

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
Volume 14, Issue 5, Pages 263-+

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nrgastro.2017.34

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Funding

  1. SUCCESS
  2. Crohn's and Colitis Foundation of America [362048]

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Disruption of the microbiota during early life can have important consequences for infant health outcomes; in particular, antibiotic usage is linked to an increased risk of pneumonia. A new study has identified cellular and molecular mediators involved in the crosstalk between early-life gut bacterial colonization and development of lung immunity against pneumonia in newborn mice.

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