4.6 Editorial Material

Romosozumab - on track or derailed?

Journal

NATURE REVIEWS ENDOCRINOLOGY
Volume 13, Issue 12, Pages 697-+

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nrendo.2017.136

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Funding

  1. NIH [AG004875, AG048792, AR027065]

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Romosozumab, a recently developed sclerostin inhibitor, stimulates bone formation and inhibits bone resorption, thereby markedly increasing bone mass and reducing fracture risk. But will a red flag regarding possible adverse cardiovascular events derail this promising new drug for osteoporosis?

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