Journal
NATURE REVIEWS CLINICAL ONCOLOGY
Volume 15, Issue 3, Pages 129-131Publisher
NATURE PORTFOLIO
DOI: 10.1038/nrclinonc.2017.174
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Funding
- CANCER-ID, an Innovative Medicines Initiative Joint Undertaking [115749]
- European Union's Seventh Framework Program
- EFPIA
- European Research Council [269081 DISSECT]
- Fashion Footwear Charitable Foundation of New York/QVC Presents Shoes on Sale
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We posit that disseminating tumour cells detected in the bone marrow or in the circulation are either cancer stem cells with full metastatic potential, tumour-bulk cells, or dormant cancer cells. This model has both therapeutic and diagnostic implications, raising concern over inadequate treatment as well as the possibility of overtreatment resulting from overdiagnosis.
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