Journal
GELS
Volume 4, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/gels4040082
Keywords
biofabrication; bioprinting; hyaluronic acid
Categories
Funding
- German Research Foundation (DFG) [TRR225]
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In this study, we evaluate hydrogels based on oxidized hyaluronic acid, cross-linked with adipic acid dihydrazide, for their suitability as bioinks for 3D bioprinting. Aldehyde containing hyaluronic acid (AHA) is synthesized and cross-linked via Schiff Base chemistry with bifunctional adipic acid dihydrazide (ADH) to form a mechanically stable hydrogel with good printability. Mechanical and rheological properties of the printed and casted hydrogels are tunable depending on the concentrations of AHA and ADH cross-linkers.
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